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Fig. 2 | BMC Endocrine Disorders

Fig. 2

From: Tumor mutational burden presents limiting effects on predicting the efficacy of immune checkpoint inhibitors and prognostic assessment in adrenocortical carcinoma

Fig. 2

Changes in TMB levels lead metabolic reprogramming in ACC. A-E The top 5 enriched signaling pathways in high-TMB group. F-J The top 5 enriched signaling pathways in low-TMB group. H The functional enrichment analyses of 30 most frequently mutated genes in ACC. I The KEGG analyses of 30 most frequently mutated genes in ACC. TMB, tumor mutational burden; BP, biological process; CC, cellular component; MF, molecular function; KEGG, Kyoto encyclopedia of genes and genomes

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BMC Endocrine Disorders

ISSN: 1472-6823

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