Fig. 1

Study design. 64 patients were randomly assigned to the combined therapy group (32 patients), which received combination therapy with BPS (60 μg/day) and aspirin (100 mg/day), or to the control group (32 patients), which only received aspirin (100 mg/day). After randomization, the patients were followed up at year 0, 1, 2, 3, 4, and 5. BPS: beraprost sodium