Table 5 Association between TG-Ab and thyroid immune related adverse effect and subgroup analysis
|  | Positive Tg-Ab (N = 4) | Negative Tg-Ab (N = 16) | P-value |
|---|---|---|---|
Presence of thyroid irAE | Â | Â | 0.591 |
 Thyroid irAE | 3 (75.0%) | 8 (50.0%) |  |
 No thyroid irAE | 1 (25.0%) | 8 (50.0%) |  |
Type of thyroid irAE | |||
 Newly developed overt hypothyroidism | 1 (25.0%) | 4 (25.0%) | 1.000 |
 Worsened hypothyroidism | 2 (50.0%) | 1 (6.2%) | 0.088 |
 Subclinical hyperthyroidism | 0 (0%) | 3 (18.8%) | 1.000 |