|
Variable
|
Grade 0 (n = 79)
|
Grade 1 (n = 199)
|
Grade 2 (n = 202)
|
Grade 3 (n = 80)
|
P
|
|---|
|
TG (mmol/L)
|
1.86 (1.13–2.93)c#
|
1.74 (1.13–2.71)e#
|
1.57 (1.07–2.40)
|
1.385 (0.92–2.12)
|
0.016*
|
|
HDL-C (mmol/L)
|
0.99 (0.82–1.16)
|
1.015 (0.84–1.16)
|
1.025 (0.87–1.22)
|
1.07 (0.93–1.32)
|
0.069
|
|
Cr (μmol/L)
|
59.1 (48.90–68.20)
|
63.25 (54.18–76.98)e#
|
61.95 (51.40–76.28)f##
|
73.5 (59.53–88.00)c##
|
0.000*
|
|
CysC (mg/L)
|
0.78 (0.67–0.89)a##
|
0.935 (0.77–1.21)e##
|
0.935 (0.80–1.18)bf##
|
1.09 (0.90–1.47)c##
|
0.000*
|
|
Hcy (μmol/L)
|
10.03 (7.21–12.47)c##
|
9.91 (7.81–13.26)
|
9.77 (8.22–12.88)f##
|
12.1 (9.55–15.79)e##
|
0.001*
|
|
ACR (mg/g)
|
12.35 (5.24–33.89)c##
|
14.46 (5.83–73.43)e#
|
16.63 (5.62–109.55)f#
|
51.21 (16.64–296.16)
|
0.005*
|
|
eGFR (ml/min)
|
109.59 (98.39–120.75)
|
97.9 (84.92–110.34)ae##
|
96 (80.98–108.94)bf##
|
84.84 (64.43–100.41)c##
|
0.000*
|
|
MAU (mg/L)
|
10.6 (5.34–25.60)c##
|
11.8 (5.15–62.00)e##
|
12.65 (4.36–51.03)f##
|
47.1 (9.39–239.50)
|
0.001*
|
|
α-MG (mg/L)
|
9.96 (55.25–15.73)c##
|
12.6 (5.30–25.80)
|
10.5 (5.01–24.10)f#
|
19.1 (7.79–34.30)
|
0.004*
|
|
Tf (mg/L)
|
2 (2.00–2.00)c##
|
2 (2.00–4.46)e#
|
2 (2.00–2.92)f##
|
2.12 (2.00–14.00)
|
0.000*
|
|
U-Ig G (mg/L)
|
3.75 (3.00–10.19)c##
|
5.36 (3.00–13.75)e#
|
4.36 (3.00–11.40)f##
|
9.15 (4.03–36.10)
|
0.001*
|
|
NEUT(109/L)
|
3.305 (2.70–4.08)
|
3.5 (2.70–4.34)
|
3.62 (2.67–4.52)
|
3.74 (2.80–4.60)
|
0.468
|
|
LY(109/L)
|
1.935 (1.45–2.54)
|
1.66 (1.25–2.17)a#
|
1.69 (1.25–2.04)b#
|
1.51 (1.26–1.84)c##
|
0.001*
|
|
NLR
|
1.64 (1.40–2.24)
|
2.01 (1.56–2.72)a#
|
2.13 (1.56–2.86)b##
|
2.415 (1.69–3.20)c##
|
0.000*
|
|
CRP (mg/L)
|
0.7 (0.50–1.80)
|
0.8 (0.50–2.58)
|
0.9 (0.50–2.60)
|
1 (0.60–7.60)c#
|
0.033*
|
|
HOMA-IR
|
1.86 (1.37–6.40)
|
1.82 (1.18–3.43)
|
2.005 (1.28–3.07)
|
0.93 (0.52–1.42)
|
0.257
|
|
PFG (mmol/L)
|
8.47 (6.38–11.35)
|
8.3 (6.41–10.17)
|
7.94 (5.94–10.53)
|
8.425 (6.25–11.53)
|
0.394
|
|
FINS (mIU/L)
|
6.78 (3.85–14.75)
|
7.005 (3.36–10.260
|
5.84 (3.93–8.59)
|
3.57 (2.29–4.46)
|
0.302
|
|
C-Peptide (nmol/L)
|
0.666 (0.45–0.83)
|
0.7275 (0.48–0.96)
|
0.646 (0.50–0.87)
|
0.554 (0.42–0.69)
|
0.158
|
|
2hC-peptide (nmol/L)
|
1.6 (1.22–2.47)
|
1.85 (1.29–2.53)
|
1.59 (1.10–2.10)
|
1.3 (0.79–2.06)
|
0.142
|
|
HbA1c(%)
|
9 (7.08–10.48)
|
8.35 (6.63–11.08)
|
7.8 (6.70–10.30)
|
7.35 (6.10–9.88)
|
0.103
|
- * The progressive significance level was 0.05. Significance of pared comparison after adjustment #P < 0.05; significance of paired comparison after adjustment ##P < 0.01. a comparison of grades 0 and 1; b comparison between grades 0 and 2; c comparison of grades 0 and 3; d comparison between levels 1 and 2; e comparison between levels 1 and 3; f comparison of levels 2 and 3
