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Table 2 Inflammatory indices, oxidative stress markers and lipid profile between Ins/Ins Homozygous vs. Del allele carriers

From: Deletion allele of Apo B gene is associated with higher inflammation, oxidative stress and dyslipidemia in obese type 2 diabetic patients: an analytical cross-sectional study

Variable

Patients

Non-obese

n = 90

Obese

n = 72

Total

n = 162

Polymorphisms

Ins/Ins

n = 60

Del carrier

n = 30

Ins/Ins

n = 47

Del carrier

n = 25

Ins/Ins

n = 107

Del carrier

n = 55

IL-18, pg/ml

240.65 ± 1.11

247.11 ± 1.10

254.44 ± 1.12

255.38 ± 1.12

246.60 ± 1.12

250.84 ± 1.11

PTX3, ng/ml

2.71 ± 1.17

2.54 ± 1.27

2.50 ± 1.22

2.56 ± 1.19

2.61 ± 1.20

2.55 ± 1.24

hs-CRP, mg/ml

1.33 ± 3.20

1.13 ± 2.92

1.80 ± 2.66 ‡

2.52 ± 1.77

1.51 ± 2.98

1.64 ± 2.61

Cu/Zn SOD, U/ml

0.14 ± 1.37

0.15 ± 1.36

0.13 ± 1.49

0.12 ± 1.31

0.14 ± 1.43

0.13 ± 1.36

TAC, g/dl

2.55 ± 1.26

2.39 ± 1.26

2.36 ± 1.19‡

2.21 ± 1.16

2.46 ± 1.23

2.30 ± 1.22

8-IF2α, pg/ml

72.01 ± 1.09

69.77 ± 1.08

73.01 ± 1.09

74.25 ± 1.06

72.44 ± 1.09

71.77 ± 1.08

HDL.C, mg/dl

50.01 ± 1.23

54.52 ± 1.22

51.68 ± 1.22

54.45 ± 1.27

50.74 ± 1.23 †

54.48 ± 1.24

LDL.C, mg/dl

111.11 ± 40.7

110.30 ± 29.45

105.91 ± 29.82†,‡

125.48 ± 47.83

108.83 ± 36.3 ‡

117.20 ± 39.25

LDL.C/HDL.C ratio

2.19 ± 0.75

2.05 ± 0.65

2.09 ± 0.68 ‡

2.25 ± 0.58

2.15 ± 0.72

2.14 ± 0.62

TC, mg/dl

197.51 ± 1.170

195.52 ± 1.55

188.75 ± 1.42

194.80 ± 1.52

193.64 ± 1.58

195.20 ± 1.53

TG, mg/dl

147.94 ± 1.22

141.67 ± 1.83

138 ± 1.69†, ‡

191.7 ± 1.76

143.44 ± 1.70

162.96 ± 1.82

  1. †Significant difference between the two polymorphisms in the crude model;‡ Significant difference between the two polymorphisms adjusted for baseline parameters
  2. IL-18 interleukin-18, PTX pentrexin-3, hs-CRP high sensitivity-C reactive protein, CU/ZN SOD superoxide dismutase, TAC total antioxidant capacity, 8-IF2α 8-isoprostane F2α, HDL-C high density lipoprotein. Cholesterol, LDL-C low density lipoprotein. Cholesterol, TG triglyceride, TC total cholesterol
  3. Data are presented as mean (± SD)
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BMC Endocrine Disorders

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