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Table 2 Inflammatory indices, oxidative stress markers and lipid profile between Ins/Ins Homozygous vs. Del allele carriers

From: Deletion allele of Apo B gene is associated with higher inflammation, oxidative stress and dyslipidemia in obese type 2 diabetic patients: an analytical cross-sectional study

Variable Patients
Non-obese
n = 90
Obese
n = 72
Total
n = 162
Polymorphisms Ins/Ins
n = 60
Del carrier
n = 30
Ins/Ins
n = 47
Del carrier
n = 25
Ins/Ins
n = 107
Del carrier
n = 55
IL-18, pg/ml 240.65 ± 1.11 247.11 ± 1.10 254.44 ± 1.12 255.38 ± 1.12 246.60 ± 1.12 250.84 ± 1.11
PTX3, ng/ml 2.71 ± 1.17 2.54 ± 1.27 2.50 ± 1.22 2.56 ± 1.19 2.61 ± 1.20 2.55 ± 1.24
hs-CRP, mg/ml 1.33 ± 3.20 1.13 ± 2.92 1.80 ± 2.66 2.52 ± 1.77 1.51 ± 2.98 1.64 ± 2.61
Cu/Zn SOD, U/ml 0.14 ± 1.37 0.15 ± 1.36 0.13 ± 1.49 0.12 ± 1.31 0.14 ± 1.43 0.13 ± 1.36
TAC, g/dl 2.55 ± 1.26 2.39 ± 1.26 2.36 ± 1.19 2.21 ± 1.16 2.46 ± 1.23 2.30 ± 1.22
8-IF2α, pg/ml 72.01 ± 1.09 69.77 ± 1.08 73.01 ± 1.09 74.25 ± 1.06 72.44 ± 1.09 71.77 ± 1.08
HDL.C, mg/dl 50.01 ± 1.23 54.52 ± 1.22 51.68 ± 1.22 54.45 ± 1.27 50.74 ± 1.23 54.48 ± 1.24
LDL.C, mg/dl 111.11 ± 40.7 110.30 ± 29.45 105.91 ± 29.82, 125.48 ± 47.83 108.83 ± 36.3 117.20 ± 39.25
LDL.C/HDL.C ratio 2.19 ± 0.75 2.05 ± 0.65 2.09 ± 0.68 2.25 ± 0.58 2.15 ± 0.72 2.14 ± 0.62
TC, mg/dl 197.51 ± 1.170 195.52 ± 1.55 188.75 ± 1.42 194.80 ± 1.52 193.64 ± 1.58 195.20 ± 1.53
TG, mg/dl 147.94 ± 1.22 141.67 ± 1.83 138 ± 1.69†, ‡ 191.7 ± 1.76 143.44 ± 1.70 162.96 ± 1.82
  1. Significant difference between the two polymorphisms in the crude model; Significant difference between the two polymorphisms adjusted for baseline parameters
  2. IL-18 interleukin-18, PTX pentrexin-3, hs-CRP high sensitivity-C reactive protein, CU/ZN SOD superoxide dismutase, TAC total antioxidant capacity, 8-IF2α 8-isoprostane F2α, HDL-C high density lipoprotein. Cholesterol, LDL-C low density lipoprotein. Cholesterol, TG triglyceride, TC total cholesterol
  3. Data are presented as mean (± SD)