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Table 4 Association of serum EV ARG 1 with diabetic medication and newly diagnosed T2DM in fully adjusted models

From: Elevated serum extracellular vesicle arginase 1 in type 2 diabetes mellitus: a cross-sectional study in middle-aged and elderly population

EV ARG 1 (per 10 pg/mL increase)

Newly diagnosed T2DM (n = 45)

T2DM with diabetic medication (n = 28)

OR (95%CI)

P value

OR (95%CI)

P value

Unadjusted

1.257 (1.110–1.422)

< 0.001**

1.366 (1.147–1.628)

< 0.001**

Model 1

1.290 (1.124–1.480)

< 0.001**

1.490 (1.201–1.849)

< 0.001**

Model 2

1.272 (1.086–1.490)

0.003*

1.563 (1.160–2.106)

0.003*

Model 3

1.335 (1.096–1.625)

0.004*

1.635 (1.139–2.347)

0.008*

  1. EV Extracellular vesicles, T2DM Type 2 diabetes mellitus, ARG 1 Arginase 1, SBP Systolic blood pressure, BMI Body Mass Index, TG Triglyceride, TC Total cholesterol, hs-CRP High-sensitivity C-reactive protein, OR Odds Ratio, CI Confidence Interval
  2. Model 1: adjusted for age, sex, BMI;
  3. Model 2: adjusted for Model 1 + age, sex, BMI, SBP, smoking, drinking, TC, hs-CRP and TG
  4. Model 3: adjusted for Model 2 + coronary heart disease
  5. *p < 0.05, **p < 0.001
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BMC Endocrine Disorders

ISSN: 1472-6823

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