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Table 1 Clinical characteristics of all obese with NAFLD children

From: Effect of growth hormone therapy on liver enzyme and other cardiometabolic risk factors in boys with obesity and nonalcoholic fatty liver disease

Variable rhGH group
(n = 22)
control group
(n = 22)
p value
Age (yr) 12.04 ± 1.56 11.48 ± 1.78 0.272
Prepuberty/Puberty, (n) 16/6 15/7 0.741▲
BMI SDS 2.56 ± 0.65 2.75 ± 0.61 0.321
CRP(mg/L) 1.75 ± 1.06 2.06 ± 1.22 0.378
ALT(U/L) 24.50(14.75, 46.00) 26.53(17.00, 60.25) 0.452▲
AST(U/L) 25.50(22.00, 29.75) 24.50(21.50, 34.25) 0.953▲
GGT(U/L) 21.50(17.00, 30.00) 28.00(21.00, 31.75) 0.09▲
TC(mmol/L) 4.57 ± 0.60 4.46 ± 0.97 0.654
HDL-C (mmol/L) 1.24(1.07, 1.40) 1.20(1.07, 1.37) 0.717#
LDL-C (mmol/L) 2.71 ± 0.45 2.68 ± 0.79 0.870
TG(mmol/L) 1.32(0.84, 1.87) 1.21(0.92, 1.58) 0.988#
UA(μmol/L) 381.05 ± 112.52 370.90 ± 68.55 0.720
Insulin(uIU/mL) 24.13 ± 11.41 25.91 ± 13.01 0.631
FBG(mmol/L) 5.17 ± 0.39 5.18 ± 0.38 0.972
HOMA-IR 5.58 ± 2.79 5.99 ± 3.13 0.648
WBISI 3.22 ± 1.16 2.84 ± 1.52 0.349
HbA1c (%) 5.68 ± 0.24 5.66 ± 0.34 0.839
  1. # p value reported for log transformed values, but values in the table represent as the median (interquartile range) ▲Mann–Whitney U test or chi square test
  2. * p < 0.05
  3. Abbreviations: BMI SDS body mass index standard deviation scores, CRP C reactive protein, ALT Alanine aminotransferase, AST Aspartate aminotransferase, GGT Gamma-glutamyl transferase, TC Total cholesterol, HDL-C High density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol, TG Triglycerides, UA Uric acid, FBG Fasting blood glucose, HOMA-IR Homeostasis model assessment of IR, WBISI Whole body insulin sensitivity index, HbA1c Glycosylated haemoglobin