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Table 4 Associations between the Sirt1 rs7895833 and anthropometric and metabolic characteristics

From: Association of genetic variants in the Sirt1 and Nrf2 genes with the risk of metabolic syndrome in a Chinese Han population

 

AA(56)

AG(285)

GG(349)

Additive effect (AA VS. AG VS. GG)

P1

Dominant effect (AA+AG VS. GG)

P2

BMI(kg/m2)

24.18±3.25

23.42±2.89

23.55±3.05

0.007±0.022

0.736

0.006±0.017

0.719

WC (cm)

80.67±8.86

78.28±9.30

78.38±9.10

0.079±0.066

0.231

-0.058±0.052

0.265

WHR

0.89±0.06

0.87±0.07

0.87±0.07

6.922±5.894

0.241

5.069±4.614

0.272

Fat% (%)

29.96±8.09

28.99±6.60

29.75±7.58

0.005±0.007

0.448

0.006±0.005

0.26

SFA (cm2)

157.3(116.3,224)

153.6(117.95,202.6)

161.1(119.1,211.1)

0±0.001

0.785

-0.00007±0.001

0.896

VFA (cm2)

81.52(61.72,112.63)

73.59(48.85,112.8)

73.4(50.53,111.25)

0±0.001

0.669

0±0.001

0.634

SBP (mm Hg)

123.12±15.79

122.07±16.01

122.55±15.51

0.001±0.003

0.568

0.00002±0.002

0.99

DBP (mm Hg)

79.45±9.34

80.81±9.97

80.47±9.33

-0.003±0.004

0.46

-0.001±0.003

0.868

FPG (mmol/L)

4.95(4.47,5.87)

4.84(4.46,5.34)

4.84(4.46,5.31)

0.039±0.037

0.298

0.011±0.029

0.702

2h PG (mmol/L)

5.36(4.35,9.4)

5.5(4.51,6.9)

5.45(4.51,7.15)

0.003±0.013

0.807

0.004±0.01

0.692

HOMA-IR

4.33(2.79,6.35)

3.96(3,5.13)

3.89(2.93,5.42)

-0.017±0.014

0.226

0.023±0.011

0.035*

HbA1c (%)

5.65(5.33,6.08)

5.6(5.3,6)

5.7(5.4,6)

0.033±0.053

0.542

0.018±0.042

0.664

TC (mmol/L)

5.32±1.10

5.56±1.08

5.64±1.18

-0.117±0.055

0.033*

-0.104±0.043

0.016*

TG (mmol/L)

1.42(0.91,2.22)

1.31(0.96,1.89)

1.3(0.97,1.83)

-0.012±0.022

0.602

-0.01±0.017

0.563

HDL-C(mmol/L)

1.39±0.39

1.47±0.37

1.45±0.35

0.002±0.089

0.979

-0.017±0.069

0.811

LDL-C(mmol/L)

2.51±0.61

2.36±0.57

2.24±0.61

0.338±0.098

0.001*

0.272±0.077

<0.001*

UA(mmol/L)

294.2(219.9,332.8)

267.4(213.9,332.8)

273.4(219.9,329.8)

0.001±0

0.094

0±0

0.23

CREA(μmol/L)

70.72(61.88,79.56)

70.72(61.88,79.56)

61.88(61.88,79.56)

-0.004±0.002

0.088

-0.002±0.002

0.274

BUN(mmol/L)

5.87±1.32

5.64±1.36

5.84±1.35

0.022±0.02

0.256

0.025±0.015

0.111

UACR(mg/mmol)

4.73(3.33,7.75)

4.56(2.95,7.27)

4.95(3.39,8.14)

0±0

0.466

0.0001±0

0.621

  1. Bold indicated significant correlation
  2. * P < 0.05