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Table 4 Associations between the Sirt1 rs7895833 and anthropometric and metabolic characteristics

From: Association of genetic variants in the Sirt1 and Nrf2 genes with the risk of metabolic syndrome in a Chinese Han population

  AA(56) AG(285) GG(349) Additive effect (AA VS. AG VS. GG) P1 Dominant effect (AA+AG VS. GG) P2
BMI(kg/m2) 24.18±3.25 23.42±2.89 23.55±3.05 0.007±0.022 0.736 0.006±0.017 0.719
WC (cm) 80.67±8.86 78.28±9.30 78.38±9.10 0.079±0.066 0.231 -0.058±0.052 0.265
WHR 0.89±0.06 0.87±0.07 0.87±0.07 6.922±5.894 0.241 5.069±4.614 0.272
Fat% (%) 29.96±8.09 28.99±6.60 29.75±7.58 0.005±0.007 0.448 0.006±0.005 0.26
SFA (cm2) 157.3(116.3,224) 153.6(117.95,202.6) 161.1(119.1,211.1) 0±0.001 0.785 -0.00007±0.001 0.896
VFA (cm2) 81.52(61.72,112.63) 73.59(48.85,112.8) 73.4(50.53,111.25) 0±0.001 0.669 0±0.001 0.634
SBP (mm Hg) 123.12±15.79 122.07±16.01 122.55±15.51 0.001±0.003 0.568 0.00002±0.002 0.99
DBP (mm Hg) 79.45±9.34 80.81±9.97 80.47±9.33 -0.003±0.004 0.46 -0.001±0.003 0.868
FPG (mmol/L) 4.95(4.47,5.87) 4.84(4.46,5.34) 4.84(4.46,5.31) 0.039±0.037 0.298 0.011±0.029 0.702
2h PG (mmol/L) 5.36(4.35,9.4) 5.5(4.51,6.9) 5.45(4.51,7.15) 0.003±0.013 0.807 0.004±0.01 0.692
HOMA-IR 4.33(2.79,6.35) 3.96(3,5.13) 3.89(2.93,5.42) -0.017±0.014 0.226 0.023±0.011 0.035*
HbA1c (%) 5.65(5.33,6.08) 5.6(5.3,6) 5.7(5.4,6) 0.033±0.053 0.542 0.018±0.042 0.664
TC (mmol/L) 5.32±1.10 5.56±1.08 5.64±1.18 -0.117±0.055 0.033* -0.104±0.043 0.016*
TG (mmol/L) 1.42(0.91,2.22) 1.31(0.96,1.89) 1.3(0.97,1.83) -0.012±0.022 0.602 -0.01±0.017 0.563
HDL-C(mmol/L) 1.39±0.39 1.47±0.37 1.45±0.35 0.002±0.089 0.979 -0.017±0.069 0.811
LDL-C(mmol/L) 2.51±0.61 2.36±0.57 2.24±0.61 0.338±0.098 0.001* 0.272±0.077 <0.001*
UA(mmol/L) 294.2(219.9,332.8) 267.4(213.9,332.8) 273.4(219.9,329.8) 0.001±0 0.094 0±0 0.23
CREA(μmol/L) 70.72(61.88,79.56) 70.72(61.88,79.56) 61.88(61.88,79.56) -0.004±0.002 0.088 -0.002±0.002 0.274
BUN(mmol/L) 5.87±1.32 5.64±1.36 5.84±1.35 0.022±0.02 0.256 0.025±0.015 0.111
UACR(mg/mmol) 4.73(3.33,7.75) 4.56(2.95,7.27) 4.95(3.39,8.14) 0±0 0.466 0.0001±0 0.621
  1. Bold indicated significant correlation
  2. * P < 0.05