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Table 3 Somatropin daily posology (mg/day) prescribed in GHD-adults according to the diagnosis, as reported to the RNAOC-web platform by the clinical specialist centres from January 1st 2011 to December 31st 2019

From: Somatropin therapy in italian adults with growth hormone deficiency

Adulthood diagnoses Starting daily posology (mg/day) 5-years daily posology (mg/day)
  Mean SD (±) Mean SD (±)
Hypopituitarism:
idiopathic, autoimmune hypophysitis, post-cranio-encephalic trauma, surgery or irradiation for sellar or parasellar tumors, empty sella, Sheehan syndrome
0.337 0.227 0.348 0.266
Hypopituitarism post total or partial hypophysectomy 0.296 0.188 0.304 0.192
Congenital GH deficiency with demonstrated genetic defect 0.424 0.128 - -
Not included in Note#39 0.206 0.082 0.229 0.049
All diagnoses 0.320 0.212 0.329 0.238