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Table 2 Comparison of clinical data between patients with Gitelman syndrome and Bartter syndrome

From: Different roles of the RAAS affect bone metabolism in patients with primary aldosteronism, Gitelman syndrome and Bartter syndrome

Variable

Gits group (20 cases)

Bartter group (17 cases)

P

Sex (male/female)

11/9

8/9

0.630 (χ2)

Age, y

36.3 ± 15.5

36 ± 13.9

0.951

BMI, kg/m2

21.99 ± 4.57

21.54 ± 4.66

0.770

Serum potassium, mmol/L

2.96 ± 0.31

3.10 ± 0.50

0.345

Albumin, g/L

41.70 ± 3.19

43.00 ± 2.76

0.224

Albumin-corrected serum calcium, mmol/L

2.34 ± 0.17

2.34 ± 0.23

1.000

Serum phosphate, mmol/L

1.29 ± 0.20

1.19 ± 0.21

0.193

Serum creatinine, umol/L

57.7 ± 16.81

64.11 ± 16.49

0.251

Serum magnesium, mmol/L

0.62 ± 0.16

0.74 ± 0.16

0.025

Serum PTH, pmol/L

3.58 ± 3.13

3.67 ± 3.13

0.932

Serum 25-OHVD, nmol/L

44.55 ± 18.88

43.30 ± 25.40

0.864

Serum AKP, U/L

61.00 (52.25, 67.50)

58.00 (46.50, 71.50)

0.636 (Non-parametric)

Urinary calcium, mmol/24 h

0.53 (0.27, 0.94)

1.36 (0.61, 3.70)

< 0.01 (Non-parametric)

Urinary magnesium, mmol/24 h

4.37 ± 1.43

3.92 ± 2.01

0.432

Urinary potassium, mmol/24 h

94.73 ± 52.27

83.82 ± 47.15

0.513

Blood gas PH, (7.35–7.45)

7.47 ± 0.031

7.47 ± 0.033

0.814

Serum renin, uIU/mL

4.53 (1.97, 73.52)

5.48 (3.09, 18.26)

0.962 (Non-parametric)

Serum aldosterone, ng/dL

17.35 (12.83, 19.65)

15.42 (11.60, 24.10)

0.924 (Non-parametric)

L1-L4, BMD, g/cm2

1.209 ± 0.170

1.095 ± 0.120

0.028

Femoral neck, BMD, g/cm2

1.008 ± 0.148

0.927 ± 0.155

0.114

Total hip, BMD, g/cm2

1.057 ± 0.160

1.003 ± 0.153

0.303

  1. The measurement data with a non-normal distribution were expressed by M (P25, P75), others were expressed as −x ± s