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Table 2 Association between CLT and clinicopathological characteristics in patients < 55 years

From: Coexisting CLT in PTC is an independent predictor of tumor aggressiveness for patients aged under 55: a retrospective analysis of 635 patients

Characteristics Total non-CLT(%) CLT-coexisted(%) OR(95%CI) P value
Number of patients 515 366 (71.1) 149 (28.9)   
Sex
Female 383 250 (68.3) 133 (89.3) 3.9 (2.2–6.8)  < 0.001
Male 132 116 (31.7) 16 (10.7)   
#Mean rank of lesion size   247.31 284.25   0.005
0 < size  ≤ 1 cm   240 (53.7) 85 (45.2)   
1 cm < size ≤ 2 cm   95 (21.3) 38 (20.2)
2 cm < size ≤ 4 cm   108 (24.2) 61 (32.4)
4 cm < size   4 (0.9) 4 (2.1)
Small lesion (Dmax ≤ 1 cm) 264 200 (54.6) 64 (43.0) 1.6 (1.2–2.4) 0.02
Extrathyroidal extension 116 74 (20.2) 42 (28.2) 1.5 (1.1–2.4) 0.04
CLNM 273 202 (55.2) 71 (47.7) 0.7 (0.5–1.1) 0.12
LLNM 53 39 (10.7) 14 (9.4) 0.9 (0.5–1.7) 0.67
CLNM of small lesions 139 114 (47.3) 25 (29.4) 0.5 (0.3–0.8) 0.004
TNM stage
I 515 366 (71.1) 149 (28.9)   
I-IV 0     
Multifocality 152 102 (27.9) 50 (34.0) 1.3 (0.9–2.0) 0.27
  1. CLNM central lymph node metastasis, LLNM lateral lymph node metastasis, OR odds ratio, #Mann–Whitney U test used