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Table 2 Association between CLT and clinicopathological characteristics in patients < 55 years

From: Coexisting CLT in PTC is an independent predictor of tumor aggressiveness for patients aged under 55: a retrospective analysis of 635 patients

Characteristics

Total

non-CLT(%)

CLT-coexisted(%)

OR(95%CI)

P value

Number of patients

515

366 (71.1)

149 (28.9)

  

Sex

Female

383

250 (68.3)

133 (89.3)

3.9 (2.2–6.8)

 < 0.001

Male

132

116 (31.7)

16 (10.7)

  

#Mean rank of lesion size

 

247.31

284.25

 

0.005

0 < size  ≤ 1 cm

 

240 (53.7)

85 (45.2)

  

1 cm < size ≤ 2 cm

 

95 (21.3)

38 (20.2)

2 cm < size ≤ 4 cm

 

108 (24.2)

61 (32.4)

4 cm < size

 

4 (0.9)

4 (2.1)

Small lesion (Dmax ≤ 1 cm)

264

200 (54.6)

64 (43.0)

1.6 (1.2–2.4)

0.02

Extrathyroidal extension

116

74 (20.2)

42 (28.2)

1.5 (1.1–2.4)

0.04

CLNM

273

202 (55.2)

71 (47.7)

0.7 (0.5–1.1)

0.12

LLNM

53

39 (10.7)

14 (9.4)

0.9 (0.5–1.7)

0.67

CLNM of small lesions

139

114 (47.3)

25 (29.4)

0.5 (0.3–0.8)

0.004

TNM stage

I

515

366 (71.1)

149 (28.9)

  

I-IV

0

    

Multifocality

152

102 (27.9)

50 (34.0)

1.3 (0.9–2.0)

0.27

  1. CLNM central lymph node metastasis, LLNM lateral lymph node metastasis, OR odds ratio, #Mann–Whitney U test used