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Table 1 Characteristics study population – non-PTX vs PTX

From: The effect of parathyroidectomy compared to non-surgical surveillance on kidney function in primary hyperparathyroidism: a nationwide historic cohort study

 

All

non-PTX

PTX

p

Normal range

(n = 3585)

(n = 1608)

(n = 1977)

 

Sex, n (%)

0.024*

Male

 

752 (21%)

310 (19%)

442 (22%)

 

Female

 

2833 (79%)

1298 (81%)

1535 (78%)

 

Age at diagnosis, years

 

67 (57;76)

74 (64;81)

62 (54;70)

< 0.001*

Time difference from diagnosis to follow-up, days

 

433 (364;594)

365 (337;386)

575 (480;734)

< 0.001*

Biochemistry Baseline

P-Creatinin, μmol/L

45–90

75 (64;91)

79 (65;98)

73 (63;87)

< 0.001*

P-Ca (ionized), mmol/L

1.18–1.32

1.43 (1.38;1.49)

1.40 (1.36;1.44)

1.45 (1.40;1.53)

< 0.001*

P-Ca (total), mmol/L

2.20–2.55

2.67 (2.58;2.78)

2.62 (2.54;2.71)

2.72 (2.63;2.84)

< 0.001*

P-PTH, pmol/L

1.6–6.9

10.90 (8.29;15;36)

9.80 (7.71;13.45)

11.85 (9.00;16.90)

< 0.001*

eGFR, mL/min

> 90

76 (59;91)

69 (52;86)

81 (66;95)

< 0.001*

Biochemistry Follow-up

P-Creatinin, μmol/L

45–90

77 (65;93)

79 (65;98)

76 (65;90)

< 0.001*

P-Ca (ionized), mmol/L

1.18–1.32

1.36 (1.28;1.42)

1.38 (1.33;1.43)

1.23 (1.19;1.25

< 0.001*

P-Ca (total), mmol/L

2.20–2.55

2.59 (2.47;2.70)

2.61 (2.52;2.71)

2.32 (2.23;2.39)

< 0.001*

P-PTH, pmol/L

1.6–6.9

6.5 (4.29;9.90)

9.59 (6.90;13.52)

4.80 (3.44;6.51)

< 0.001*

eGFR, mL/min

> 90

75 (57;90)

69 (51;86)

79 (63;92)

< 0.001*

  1. Results listed as number of subjects (%) or median with interquartile range (25%;75%)
  2. p-values shows results of statistical tests comparing PTX-treated and non-PTX-treated. p < 0.05 is considered as significant and is marked by *
  3. Baseline: Time of pHPT-diagnosis
  4. Follow-up: 9–15 months after respectively time of diagnosis for non-PTX group and PTX for PTX group
  5. Abbreviations: PTX parathyroidectomy, pHPT primary hyperparathyroidism, Ca calcium, PTH parathyroid hormone, eGFR estimated glomerular filtration rate