Table 4 Baseline concomitant medications used by ≥10% of adult patientsa
Medication, n (%)b | rhPTH(1-84) (n=125) | Conventional therapy (n=571) | Analysis populationc (N=696) |
|---|---|---|---|
Vitamin D and analogs | 105 (84.0) | 523 (91.6) | 628 (90.2) |
Calcitriol | 86 (68.8) | 430 (75.3) | 516 (74.1) |
Native vitamin D, including cholecalciferol and ergocalciferol | 75 (60.0) | 255 (44.7) | 330 (47.4) |
Alfacalcidol | 1 (0.8) | 55 (9.6) | 56 (8.0) |
Calcium | 96 (76.8) | 466 (81.6) | 562 (80.7) |
Calcium carbonate | 62 (49.6) | 333 (58.3) | 395 (56.8) |
Calcium citrate | 46 (36.8) | 148 (25.9) | 194 (27.9) |
Calcium, not otherwise specified | 9 (7.2) | 39 (6.8) | 48 (6.9) |
Thyroid hormone | 86 (68.8) | 424 (74.3) | 510 (73.3) |
Levothyroxine | 79 (63.2) | 417 (73.0) | 496 (71.3) |
Magnesium | 46 (36.8) | 140 (24.5) | 186 (26.7) |
Proton pump inhibitors | 26 (20.8) | 127 (22.2) | 153 (22.0) |
Benzodiazepine derivatives | 26 (20.8) | 74 (13.0) | 100 (14.4) |
HMG-CoA reductase inhibitors | 16 (12.8) | 115 (20.1) | 131 (18.8) |
Potassium | 25 (20.0) | 66 (11.6) | 91 (13.1) |
Combinations of vitamins | 23 (18.4) | 91 (15.9) | 114 (16.4) |
Antidepressants | 23 (18.4) | 56 (9.8) | 79 (11.4) |
Selective serotonin reuptake inhibitors | 22 (17.6) | 70 (12.3) | 92 (13.2) |
Platelet aggregation inhibitorsd | 10 (8.0) | 92 (16.1) | 102 (14.7) |
Glucocorticoids | 17 (13.6) | 91 (15.9) | 108 (15.5) |
Thiazides, hydrochlorothiazide | 16 (12.8) | 76 (13.3) | 92 (13.2) |
Beta-blocking agents, selective | 15 (12.0) | 67 (11.7) | 82 (11.8) |