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Table 1 Comparison of clinical data and biochemical indicators among groups

From: Associations of plasma 8-iso-prostaglandin Flevels with fasting blood glucose (FBG) and intra-abdominal fat (IAF) area in various Glycometabolism populations

Variables

NC group

Prediabetes group

New-onset

T2DM group

Non-new-onset

T2DM group

F

P

N(M/F)

53 (27/24)

41 (22/19)

29 (16/13)

37 (18/19)

Age (year)

55.42 ± 9.71

57.59 ± 7.71

57.86 ± 9.27

58.67 ± 6.46

1.173

0.322

BMI (kg/m2)

25.53 ± 3.23

27.00 ± 2.73

25.73 ± 2.94

26.29 ± 3.31

1.691

0.171

SBP (mmHg)

119.42 ± 14.86

128.15 ± 15.77#

131.62 ± 15.90#

128.30 ± 14.74#

4.853

0.003

DBP (mmHg)

77.63 ± 10.83

81.06 ± 8.99

82.72 ± 12.41

78.43 ± 10.28

1.753

0.159

WC (cm)

89.25 ± 10.58

90.76 ± 8.52

89.78 ± 9.79

93.53 ± 7.72

1.614

0.189

HC (cm)

101.29 ± 8.31

102.71 ± 6.38

99.91 ± 6.44

99.45 ± 6.92

1.420

0.239

WHR

0.88 ± 0.06

0.88 ± 0.06

0.90 ± 0.05

0.94 ± 0.06#&*

9.518

0.000

TG (mmol/L)

1.77 ± 1.04

1.79 ± 0.98

1.76 ± 0.86

2.13 ± 1.91

0.720

0.542

TC (mmol/L)

5.29 ± 1.17

5.05 ± 0.94

5.41 ± 1.18

5.55 ± 1.57

1.028

0.382

HDL-C (mmol/L)

1.47 ± 0.36

1.37 ± 0.35

1.45 ± 0.32

1.26 ± 0.24#*

3.193

0.025

LDL-C (mmol/L)

2.78 ± 0.91

2.68 ± 0.71

2.75 ± 0.78

3.04 ± 1.07

1.158

0.328

FBG (mmol/L)

5.03 ± 0.49

5.49 ± 0.71

6.06 ± 1.19#

8.38 ± 2.85#&*

34.870

0.000

2hPG(mmol/L)

6.20 ± 1.11

9.24 ± 1.13#

13.76 ± 3.03#&

13.35 ± 5.22#&

57.991

0.000

FINS (mIU/L)

8.01 ± 4.42

8.91 ± 4.56

7.60 ± 3.11

8.76 ± 6.34

0.565

0.639

2 h INS (mIU/L)

32.13 ± 20.90

67.00 ± 57.71#

47.93 ± 23.94#&

31.45 ± 34.29&*

7.634

0.000

IAF area (cm2)

83.27 ± 41.55

99.50 ± 27.95

109.07 ± 43.93#

104.25 ± 33.94#

3.697

0.013

HOMA-IR

1.81 ± 1.04

2.18 ± 1.17

2.06 ± 1.00

3.93 ± 4.12#&*

6.987

0.000

8-iso-PGF2a(pg/ml)

32.28 ± 20.09

39.02 ± 21.72

42.22 ± 25.44#

50.06 ± 31.41#

3.688

0.013

  1. Abbreviations: BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, WC waist circumference, HC hip circumference, WHR waist-hip ratio, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, FBG fasting blood glucose, 2hPG 2 h postprandial glycemia, FINS fasting insulin, 2 h INS 2 h insulin, IAF intra-abdominal fat, HOMA-IR homeostasis model assessment-insulin resistance, 8-iso-PGF2a 8-iso-prostaglandin F2a
  2. #,compared with NC group, P < 0.05; &,compared with prediabetes group, P < 0.05;*, compared with new-onset T2DM group, P < 0.05