Fig. 2From: Evolution of a refractory prolactin-secreting pituitary adenoma into a pituitary carcinoma: report of a challenging case and literature review(A) and (B) Before the first gamma knife radiosurgery (GKS) treatment, MRI in November 2012 reported that the tumor was located in the sellar and suprasellar regions. (C) and (D) Seven months after the first GKS treatment, MRI revealed that the tumor size was slightly decreased. (E) and (F) Before the second GKS treatment, MRI in November 2013 demonstrated that the tumor size increased significantly again (Knosp grade 4). (G) and (H) Eight months after the second GKS treatment, MRI in July 2014 indicated that the tumor size was reduced slightlyBack to article page