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Table 1 General clinical profiles between 3 groups

From: Deterioration of diabetic nephropathy via stimulating secretion of cytokines by atrial natriuretic peptide

Variable

Nor-MA

Micro-MA

Macro-MA

p value

N

37

23

21

Men (%)

23 (62.2)

11 (47.82)

11 (52.38)

0.533a

Age (years)

61.32 (11.69)

66.17 (13.41)

66.10 (8.68)

0.181b

BMI (kg/m2)

23.24 (20.85,26.86)

24.24 (21.97,26.67)

24.78 (22.95,27.24)

0.709b

Duration (years)

3.40 (3.49)

10.13 (6.61)

16.52 (7.90)**

< 0.001a

SBP (mmHg)

127 (13)

133 (17)

139 (17)**

0.025a

DBP (mmHg)

78 (7)

77 (8)

79 (8)

0.522a

UAE (mg/24 h)

11.94 (7.44,21.09)

96.90 (54.78,168.66)

1155.77 (854.69,1575.00)**

< 0.001a

HbA1c (%)

8.50 (7.00,10.55)

9.10 (7.00,10.20)

7.10 (6.15,8.20)*

0.018b

ALT (IU/L)

23.16 (11.78)

30.09 (40.82)

19.19 (9.14)

0.299a

AST (IU/L)

27.57 (19.13)

30.83 (26.49)

20.82 (13.53)

0.256a

TC (mmol/L)

4.78 (3.80,5.35)

4.45 (3.22,5.53)

5.26 (3.84,6.14)

0.286b

TG (mmol/L)

1.88 (1.66)

2.18 (2.05)

2.71 (2.43)

0.317a

HDL-C (mmol/L)

1.15 (0.98,1.35)

1.05 (0.92,1.36)

1.05 (0.87,1.24)

0.421b

LDL-C (mmol/L)

2.54 (1.91,3.03)

2.27 (1.37,2.84)

2.95 (1.80,3.50)

0.229b

BUN (mmol/L)

6.02 (1.26)

7.28 (3.84)

11.26 (6.41)**

< 0.001a

Cr (umol/L)

68.34 (21.80)

86.73 (57.11)

175.38 (109.76)**

< 0.001a

Na (mmol/L)

141.80 (139.45,142.85)

140.70 (139.60,142.60)

141.70 (139.10,144.15)

0.610b

K (mmol/L)

3.83 (3.60,3.99)

3.87 (3.56,4.30)

3.77 (3.34,4.36)

0.728b

Cl (mmol/L)

101.90 (100.95,102.30)

102.80 (101.10,104.90)

104.90 (102.15,107.35)**

< 0.001b

UA (umol/L)

353.00 (251.50,428.00)

298.00 (263.00,465.00)

355.00 (306.00,476.00)

0.415b

ALB(g/L)

40.50 (38.60,40.75)

41.40 (36.50,43.60)

34.80 (30.70,38.05)**

< 0.001b

  1. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, UAE urinary albumin excretion, HbA1c glycosylated hemoglobin, ALT alanine transarninase, AST aspartate transaminase, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, BUN blood urea nitrogen, Cr plasma creatinine, TC total cholesterol, TG triglycerides, UA uric acid, ALB plasma albumin
  2. Continuous variables were expressed as mean (standard deviation) and non-normally distributed variables were expressed as median (interquartile range). An ANOVA test was used to to compare differences of mean between 3 groups (a). The Kruskal-Wallis test was used to compare differences of mean between 3 groups with normal distribution (b)
  3. *p < 0.05 compared with control group,**p < 0.01 compared with control group