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Table 3 Longitudinal association of body weight changes and risk of decreased renal function (estimated glomerular filtration rate < 60 mL/min/1.73 m2) (n = 861)

From: Associations between obesity, weight change and decreased renal function in Korean type 2 diabetic patients: a longitudinal follow-up study

 

Age-adjusted

Model 1a

Model 2b

RR (95% CI)

p

RR (95% CI)

p

RR (95% CI)

p

Body weight change (%)

 Weight gain > 10

1.50 (1.12–2.01)

0.003

1.44 (1.11–2.00)

0.005

1.43 (1.11–2.00)

0.016

 5 < weight gain ≤10

1.03 (0.70–1.29)

0.710

1.03 (0.70–1.29)

0.740

1.04 (0.70–1.29)

0.634

 Stable ±5

1 (reference)

 

1 (reference)

 

1 (reference)

 

 5 < weight loss ≤10

1.07 (0.77–1.40)

0.450

1.05 (0.77–1.40)

0.457

1.07 (0.77–1.40)

0.519

 Weight loss > 10

0.98 (0.58–1.46)

0.602

0.99 (0.58–1.48)

0.702

0.98 (0.58–1.46)

0.719

  1. RR relative risk, CI confidence interval
  2. aModel 1: adjusted for age, sex, and duration of type 2 diabetes
  3. bModel 2: adjusted for Model 1 + glycated hemoglobin, total cholesterol, triglycerides, and hypertension (high blood pressure or anti-hypertensive medication use)
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BMC Endocrine Disorders

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