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Table 2 Spearman’s correlations between BMD and serum variables, including biochemical indexes, adipokines, inflammatory cytokines, BTMs and gastrointestinal hormones

From: Effects of sleeve gastrectomy on bone mass, microstructure of femurs and bone metabolism associated serum factors in obese rats

Parameter

 

Tb BMD

Ct BMD

PINP

R

0.067

− 0.527

P

0.855

0.117

BALP

R

0.317

0.117

P

0.406

0.765

OC

R

0.900*

0.100

P

0.037

0.873

NTX

R

0.631

0.703

P

0.129

0.078

CTX-1

R

−0.607

0.071

P

0.148

0.879

25(OH)D3

R

0.762*

0.524

P

0.028

0.183

PTH

R

−0.444

− 0.176

P

0.232

0.651

Insulin

R

0.071

0.452

P

0.867

0.260

GLP-1

R

−0.048

0.286

P

0.911

0.493

ghrelin

R

0.143

0.214

P

0.760

0.645

Adiponectin

R

−0.036

−0.143

P

0.939

0.760

Leptin

R

0.048

0.190

P

0.911

0.651

FGF-21

R

−0.500

0.067

P

0.170

0.865

FGF-19

R

−0.150

−0.433

P

0.700

0.244

PTP1B

R

−0.821*

0.036

P

0.023

0.939

LECT2

R

−0.545

−0.509

P

0.083

0.110

SOCS-3

R

0.095

−0.167

P

0.823

0.693

ANGPTL2

R

−0.450

−0.450

P

0.310

0.310

TNF-α

R

−0.821

0.464

P

0.023*

0.294

MCP-1

R

−0.607

−0.286

P

0.148

0.535

IL-6

R

−0.287

0.036

P

0.490

0.933

IL-1β

R

−0.600

−0.257

P

0.208

0.623

TC

R

0.311

0.098

P

0.382

0.789

TG

R

−0.381

−0.119

P

0.352

0.779

FFA

R

0.108

0.144

P

0.818

0.758

ALT

R

−0.029

0.429

P

0.957

0.397

AST

R

−0.048

0.262

P

0.911

0.531

  1. Control group n = 5, HFD sham group n = 5, HFD SG group n = 9, *P<0.05
  2. Tb BMD: the trabecular bone mineral density; Ct BMD: cortical bone mineral density; PINP: N-terminal propeptide of type I procollagen; BALP: Bone specific alkaline phosphatase; OC: Osteocalcin; NTX: N-terminal cross-linking telopeptide of type I collagen; CTX-1: C-terminal cross-linking telopeptide of type I collagen; 25(OH)D3: 25-hydroxy vitamin D3; PTH: Parathyroid hormone; GLP-1: Glucagon-like peptide-1; FGF: Fibroblast growth factor; PTP1B: Protein tyrosine phosphatase 1B; LECT2: Leukocyte cell-derived chemotaxin 2; SOCS3: Suppressor of cytokine signalling-3; ANGPTL2: Angiopoietin-like protein 2; TNF-α: Tumor necrosis factor-α; MCP-1: Monocyte chemoattractant protein-1; IL-6: Interleukin-6; IL-1β: Interleukin-1β; TC: Total cholesterol; TG: Triacylglycerol; FFA: Free fatty acid; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase