Fig. 1
From: Unique three-site compound heterozygous mutation in the WFS1 gene in Wolfram syndrome
Fundus photography and periorbital magnetic resonance images of two patients. (1) Shows the fundoscopic results of patient 1, and (2) shows the fundoscopic results of patient 2. Both figures show optic disc diffused pallid bilaterally without diabetic retinopathy. The two patients’ optic nerves were pale, and the bilateral optic nerves were thinner. A-C Bilateral optic nerve atrophy from the coronal and sagittal positions in patient 1. D-F Bilateral optic nerve atrophy from the coronal and sagittal positions in patient 2. Red arrows show the atrophic optic nerves of the two patients