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Table 2 Association of ZnT8 AAb positivity with clinical and phenotypic variables in participants with T1D

From: Zinc transporter 8 (ZnT8) autoantibody prevalence in black South African participants with type 1 diabetes

Variable

ZnT8 AAb positivity

p value

Positive (n=32)

Negative (n=151)

 

Age at diagnosis (years)

17.0 ± 6.49

21.6 ± 8.62

0.005

Duration of disease (years)

3.50 [1.00; 8.00]

7.00 [3.00; 12.0]

0.003

Gender

   

Males, % (n)

59.4 (19)

53.6 (81)

0.696

Females, % (n)

40.6 (13)

46.4 (70)

Glucose (mmol/L)

10.9 [7.10; 16.1]a

8.40 [5.40; 13.1]b

0.042

HbA1c (%)

10.9 ± 3.50

10.5 ± 3.40

0.593

BMI (kg/m2)

20.1 [19.4; 23.9]

23.9 [21.4; 28.7]

0.003

IA2 AAb positivity (%; n)

44.4 (12)c

6.2 (8)d

<0.001

GAD65 AAb positivity (%; n)

81.5 (22)c

45.0 (58)d

<0.001

  1. Results are presented as median values [interquartile range] for skewed data and as mean ± standard deviation for non-skewed data; Missing data: an = 4, bn = 10, cn = 5 and dn = 22