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Table 1 Baseline characteristics of patients according to FT3 calssification

From: Combined use of low T3 syndrome and NT-proBNP as predictors for death in patients with acute decompensated heart failure

Variable LT3S group
(n = 168)
non-LT3S group
(n = 426)
P value
Age, year 61 ± 16 57 ± 15 0.009
Male, n (%) 114 (67.9) 300 (70.4) 0.540
History, n (%)
  Hypertension 80(47.6) 189(44.4) 0.473
  Diabetes mellitus 44(26.2) 88(20.7) 0.144
  Ischemic heart disease 58(34.5) 142(33.3) 0.782
  Dilated cardiomyopathy 38(22.6) 118(27.7) 0.205
  Valvular heart disease 47(28.0) 98(23.0) 0.204
  Atrial fibrillation 82(49.1) 134(32.2) < 0.001
Physical examination
  Heart rate, beats/min 79 ± 19 79 ± 16 0.999
  Systolic blood pressure, mmHg 112 ± 19 117 ± 19 0.003
  Body mass index, kg/m2 23.0 ± 4.3 24.0 ± 4.7 0.016
NYHA functional class, n (%)    < 0.001
  II 11(6.5) 86(20.2)  
  III 68(40.5) 204(47.9)  
  IV 89(53.0) 136(31.9)  
  LVEF (%) 41.6 ± 14.1 39.6 ± 14.5 0.128
  LVEF < 40 %, n (%) 82(48.8) 235(55.2) 0.162
  LVEDD, mm 60.0 ± 13.2 62.5 ± 12.8 0.031
Laboratory results
  Hemoglobin, g/dL 126.1 ± 26.4 138.5 ± 20.8 < 0.001
  Sodium, mmol/L 138.2 ± 4.2 139.6 ± 3.3 < 0.001
  Albumin, g/dL 37.4 ± 4.8 40.5 ± 4.4 < 0.001
  Blood urea nitrogen, mmol/L 11.5 ± 6.5 8.4 ± 3.9 < 0.001
  Creatinine, umol/L 117.1 ± 57.7 96.8 ± 36.3 < 0.001
  NT-proBNP, pg/mL 3165(1441–5525) 1756(998–3263) < 0.001
Medication on presentation, n (%)
  Diuretics 134(79.8) 330(77.5) 0.542
  ACEI/ARB/ARNI 99(58.9) 236(55.4) 0.435
  β-blockers 132(78.6) 328(77.0) 0.679
  Spironolactone 106(63.1) 262(61.5) 0.719
Intravenous cardiotonic therapy
  Dopamine 121(72.0) 191(44.8) < 0.001
  Dobutamine 5(3.0) 13(3.1) 0.961
  Norepinephrine 7(4.2) 16(3.8) 0.815
  In-hospital death, n (%) 15(8.9) 12(2.8) 0.001
  One-year all cause death, n (%)a 53(34.6) 47(11.3) < 0.001
  1. aFor patients discharged alive. ACEI angiotension-converting enzyme inhibitor; ARB angiotensin receptor blocker; eGFR estimated glomerular filtration rate; FT3 free triiodothyronine; LVDD left ventricular diastolic diameter; LVEF left ventricular ejection fraction; NT-proBNP N-terminal pro-B-type natriuretic peptide; NYHA New York Heart Association