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Table 6 Interactions between CAV-1 rs3807992 and unhealthy dietary intake on CVDs risk factors

From: Interactions between Caveolin-1 (rs3807992) polymorphism and major dietary patterns on cardio-metabolic risk factors among obese and overweight women

 

β (95%CI) (AA + AG)

1(Ref) GG

 

Crude

P*

Adjusted

P**

TC (mg/dl)

6.30 (−15.08,27.96)

0.56

9.90 (− 12.33,32.14)

0.38

HDL-C (mg/dl)

3.66(− 2.78,10.11)

0.26

5.27(−1.64,12.19)

0.13

LDL (mg/dl)

−14.08 (− 28.70,0.52)

0.05

− 0.061 (−.131,0.009)

0.08

TC/HDL

−0.38(− 1.32,0.55)

0.41

− 0.29(− 1.33,0.74)

0.57

LDL/HDL

− 0.39 (− 0.75,-0.03)

0.03

−0.33 (− 0.69,0.02)

0.07

TG (mg/dl)

−70.76 (113.80,27.72)

0.001

−64.63 (103.68,25.58)

0.001

ALT(IU.L)

−2.6 (−7.26,2.05)

0.27

−8.01(−16.92,0.89)

0.07

AST (IU.L)

−0.19 (− 0.33,-0.05)

0.008

− 0.18 (− 0.33,0.04)

0.01

hs-CRP (mg/L)

−1.08(− 3.93,1.76)

0.45

− 1.59(− 4.79,1.59)

0.32

MCP-1(ng/ml)

73.43 (13.01,133.859)

0.01

82.27 (17.42,147.129)

0.01

PAI-1(ng/ml)

17.12 (−5.52,39.78)

0.13

20.96 (−2.21,44.13)

0.07

IL1B (pg/ml)

0.09 (−0.27,0.46)

0.61

−0.25 (− 0.6,0.09)

0.15

  1. Values are represented as β (95%CI)
  2. A significant p-values are indicated in bold (significance considered p < 0.05)
  3. GLM was performed to identify significant differences between tertiles of unhealthy DP and CAV-1 rs3807992
  4. P* = with unadjusted (crude) model
  5. P** = with adjustments for potential confounding factors including (Age, energy intake, physical activity, DBP)