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Table 6 Interactions between CAV-1 rs3807992 and unhealthy dietary intake on CVDs risk factors

From: Interactions between Caveolin-1 (rs3807992) polymorphism and major dietary patterns on cardio-metabolic risk factors among obese and overweight women

  β (95%CI) (AA + AG)
1(Ref) GG
 
Crude P* Adjusted P**
TC (mg/dl) 6.30 (−15.08,27.96) 0.56 9.90 (− 12.33,32.14) 0.38
HDL-C (mg/dl) 3.66(− 2.78,10.11) 0.26 5.27(−1.64,12.19) 0.13
LDL (mg/dl) −14.08 (− 28.70,0.52) 0.05 − 0.061 (−.131,0.009) 0.08
TC/HDL −0.38(− 1.32,0.55) 0.41 − 0.29(− 1.33,0.74) 0.57
LDL/HDL − 0.39 (− 0.75,-0.03) 0.03 −0.33 (− 0.69,0.02) 0.07
TG (mg/dl) −70.76 (113.80,27.72) 0.001 −64.63 (103.68,25.58) 0.001
ALT(IU.L) −2.6 (−7.26,2.05) 0.27 −8.01(−16.92,0.89) 0.07
AST (IU.L) −0.19 (− 0.33,-0.05) 0.008 − 0.18 (− 0.33,0.04) 0.01
hs-CRP (mg/L) −1.08(− 3.93,1.76) 0.45 − 1.59(− 4.79,1.59) 0.32
MCP-1(ng/ml) 73.43 (13.01,133.859) 0.01 82.27 (17.42,147.129) 0.01
PAI-1(ng/ml) 17.12 (−5.52,39.78) 0.13 20.96 (−2.21,44.13) 0.07
IL1B (pg/ml) 0.09 (−0.27,0.46) 0.61 −0.25 (− 0.6,0.09) 0.15
  1. Values are represented as β (95%CI)
  2. A significant p-values are indicated in bold (significance considered p < 0.05)
  3. GLM was performed to identify significant differences between tertiles of unhealthy DP and CAV-1 rs3807992
  4. P* = with unadjusted (crude) model
  5. P** = with adjustments for potential confounding factors including (Age, energy intake, physical activity, DBP)