Circulating ERBB3 levels are inversely associated with the risk of overweight-related hypertension: a cross-sectional study

Table 1 Characteristics of the study participants among CNT, HT and HTO groups

Characteristic	Group	CNT (n = 31)	HT(n = 33)	HTO (n = 64)	F/χ²	P
Gender	Male	18(58.1)	22(66.7)	32(50.0)	2.512	0.285
Gender	Female	13(41.9)	11(33.3)	32(50.0)	2.512	0.285
Age (year)		60.32±5.82	63.67±8.35	62.61±8.69	1.476	0.232
Blood pressure(mmHg)	SBP	122.84±13.27	148.94±15.86*	147.23±14.26*	35.19	<0.001
Blood pressure(mmHg)	DBP	74.29±9.58	83.00±9.62*	83.59±10.97*	9.18	<0.001
TC(mmol/L)		4.86±0.90	4.44±0.82	4.51±0.97	1.961	0.145
TG(mmol/L)		1.61±0.78	1.43±0.58	2.03±1.10*#	5.354	0.006
HDL-C(mmol/L)		1.53±0.36	1.51±0.38	1.40±0.24	2.414	0.094
LDL-C(mmol/L)		2.59±0.73	2.28±0.68	2.18±0.82	2.966	0.055
UA(umol/L)		360.01±88.18	329.27±80.75	385.63±95.21#	4.327	0.015
GLU(mmol/L)		5.08±0.95	5.45±0.94	5.45±1.14	1.430	0.243
BMI(kg/m²)		21.43±1.73	21.40±1.90	26.71±2.51*#	91.753	<0.001
ERBB3(ng/ml)		1.00±0.43	1.01±0.35	0.92±0.37	0.792	0.455
Current smoker	Yes	12(38.7)	14(42.4)	10(15.6)	10.003	0.007
Current smoker	No	19(61.3)	19(57.6)	54(84.4)	10.003	0.007
Current drinker	Yes	12(38.7)	12(36.4)	22(34.4)	0.174	0.917
Current drinker	No	19(61.3)	21(63.6)	42(65.6)	0.174	0.917

CNT healthy control group, HT hypertension group, HTO hypertension with overweight group, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, GLU glucose, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, UA uric acid. P: All participants had the variables analyzed by one-way ANOVA or Chi- square test among CNT, HT and HTO groups.*: p < 0.05 vs. CNT.# : p < 0.05 vs. HT

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