Impact of triglycerides and waist circumference on insulin resistance and β-cell function in non-diabetic first-degree relatives of type 2 diabetes

Table 2 Correlation of metabolic syndrome factors with diabetic parameters among FDRs of Type 2 DM

	FBG	HbA1c	Fructosamine	Insulin	HOMA-IR	HOMA-β
Age	0.15 (0.12)	0.25 (0.01)	0.14 (0.16)	−0.05 (0.60)	−0.05 (0.61)	−0.13 (0.19)
Waist Circumference	0.26 (0.009)	0.27 (0.007)	0.11 (0.25)	0.50 (6.5 × 10⁻⁸)	0.50 (8.6 × 10⁻⁸)	0.38 (9 × 10⁻⁵)
Triglyceride	0.1 (0.60)	0.2 (0.02)	0.2 (0.07)	0.5 (4.7 × 10⁻⁹)	0.5 (7.4 × 10⁻⁹)	0.5 (3.2 × 10⁻⁷)
Systolic Blood Pressure	0.11 (0.27)	0.15 (0.14)	0.05 (0.64)	0.13 (0.20)	0.13 (0.17)	0.06 (0.52)
Diastolic Blood Pressure	0.05 (0.64)	0.10 (0.30)	0.04 (0.71)	0.23 (0.02)	0.24 (0.02)	0.19 (0.05)
HDL-Cholesterol	0.076 (0.45)	0.001 (1.0)	−0.046 (0.65)	−0.149 (0.13)	−0.145 (0.14)	−0.180 (0.07)

Data are presented as R² and (p-value)
FBG fasting blood glucose, HbA1c glycated hemoglobin, HOMA-IR insulin resistance, HOMA-β β-cell function

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