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Fig. 4 | BMC Endocrine Disorders

Fig. 4

From: LncRNA HCP5 knockdown inhibits high glucose-induced excessive proliferation, fibrosis and inflammation of human glomerular mesangial cells by regulating the miR-93-5p/HMGA2 axis

Fig. 4

MiR-93-5p restoration alleviated HG-induced HGMC dysfunctions. In the NG, HG, HG + miR-93-5p and HG + miR-NC groups, (A) cell proliferation was assessed by CCK-8 assay. B and C Cell apoptosis was investigated using flow cytometry assay. D The protein levels of Cleaved-PARP and Cleaved-caspase 3 were detected using western blot. E The protein levels of FN, Col IV and Col I were detected by western blot. F The release of TNF-α, IL-6 and IL-1β was examined using ELISA kits. *P < 0.05, **P < 0.01 and ***P < 0.001

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BMC Endocrine Disorders

ISSN: 1472-6823

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