Table 2 Comparison between low TSH and normal TSH groups in patients with COVID-19 presenting with NTI
Overall (n = 150) | Low TSH (n = 27) | Normal TSH (n = 123) | P value | |
|---|---|---|---|---|
Age, y, M (IQR) | 69.5 (61,79) | 68 (62.5, 78) | 70 (60.5, 79) | 0.924 |
Gender (female n, %) | 69 (46%) | 12 (44.44%) | 57 (46.34%) | 0.858 |
Critical illness (n, %) | 66 (44%) | 20 (74.07%) | 46 (37.40%) | 0.001 |
Mortality (n, %) | 42 (28%) | 14 (51.85%) | 28 (22.76%) | 0.002 |
History of cerebropathy (n, %) | 17 (11.33%) | 4 (14.81%) | 13 (10.57%) | 0.551 |
WBC, *10^9/L, M (IQR) | 10.73 (7.795,16.795) | 14.08 (10.46, 21.2) | 10.2 (7.19, 16.37) | 0.023 |
LC, *10^9/L, M (IQR) | 1.45 (0.945,1.87) | 1.13 (0.82, 1.97) | 1.45 (0.985, 1.87) | 0.572 |
CRP, mg/L, M (IQR) | 91.2 (41.825,177.275) | 162.6 (70.9, 224.9) | 84 (36.45, 155.7) | 0.013 |
Ferroprotein, ug/L, M (IQR) | 1314.7 (631.92395.6) | 1879.35 (1042.83, 2861.8) | 1166.2 (562.35, 2147.15) | 0.047 |
PCT, ng/mL, M (IQR) | 0.19 (0.08,0.99) | 0.39 (0.115, 4.16) | 0.17 (0.08, 0.86) | 0.084 |
ALT, U/L, M (IQR) | 44.5 (22.25,73.75) | 57 (29, 69.5) | 42 (21, 76) | 0.219) |
AST, U/L, M (IQR) | 44.5 (26,75.75) | 57 (37.5, 109.5) | 42 (25, 69.5) | 0.042 |
ALB, g/L, M (IQR) | 35.05 (30.175,39.15) | 36.3 (33.5, 39.3) | 34.9 (30.15, 38.8) | 0.605 |
LDH, U/L, M (IQR) | 221 (180,282) | 279 (188, 413) | 216.5 (174, 271.5) | 0.038 |
CR, umol/L, M (IQR) | 87 (68.25,117.75) | 88 (76, 184) | 87 (67, 114.5) | 0.194 |
UREA, mmol/L, M (IQR) | 8.9 (5.7,15.85) | 14.1 (9.7, 26.35) | 7.6 (5.2, 14.2) | < 0.001 |
cTnI, pg/mL, M (IQR) | 18.05 (6.35,197.875) | 70.7 (11.2, 755.65) | 13.8 (6.2, 162.7) | 0.098 |
D2D, ug/mL FEU, M (IQR) | 5.365 (1.46,19.045) | 8.41 (2.47, 17.74) | 4.5 (1.39, 19.06) | 0.316 |
FT3, pmol/L, M (IQR) | 2.665 (2.303,2.888) | 2.68 (2.35, 2.92) | 2.66 (2.31, 2.88) | 0.696 |
FT4, pmol/L, M (IQR) | 16.05 (13.623,18.345) | 16.39 (13.53, 18.89) | 16 (13.75, 18.25) | 0.687 |
TSH, uIU/mL, M (IQR) | 0.96 (0.412,1.848) | 0.16 (0.10, 0.21) | 1.29 (0.69, 2.03) | / |