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Table 2 Comparison between low TSH and normal TSH groups in patients with COVID-19 presenting with NTI

From: Prognostic significance of low TSH concentration in patients with COVID-19 presenting with non-thyroidal illness syndrome

  Overall
(n = 150)
Low TSH
(n = 27)
Normal TSH
(n = 123)
P value
Age, y, M (IQR) 69.5 (61,79) 68 (62.5, 78) 70 (60.5, 79) 0.924
Gender (female n, %) 69 (46%) 12 (44.44%) 57 (46.34%) 0.858
Critical illness (n, %) 66 (44%) 20 (74.07%) 46 (37.40%) 0.001
Mortality (n, %) 42 (28%) 14 (51.85%) 28 (22.76%) 0.002
History of cerebropathy (n, %) 17 (11.33%) 4 (14.81%) 13 (10.57%) 0.551
WBC, *10^9/L, M (IQR) 10.73 (7.795,16.795) 14.08 (10.46, 21.2) 10.2 (7.19, 16.37) 0.023
LC, *10^9/L, M (IQR) 1.45 (0.945,1.87) 1.13 (0.82, 1.97) 1.45 (0.985, 1.87) 0.572
CRP, mg/L, M (IQR) 91.2 (41.825,177.275) 162.6 (70.9, 224.9) 84 (36.45, 155.7) 0.013
Ferroprotein, ug/L, M (IQR) 1314.7 (631.92395.6) 1879.35 (1042.83, 2861.8) 1166.2 (562.35, 2147.15) 0.047
PCT, ng/mL, M (IQR) 0.19 (0.08,0.99) 0.39 (0.115, 4.16) 0.17 (0.08, 0.86) 0.084
ALT, U/L, M (IQR) 44.5 (22.25,73.75) 57 (29, 69.5) 42 (21, 76) 0.219)
AST, U/L, M (IQR) 44.5 (26,75.75) 57 (37.5, 109.5) 42 (25, 69.5) 0.042
ALB, g/L, M (IQR) 35.05 (30.175,39.15) 36.3 (33.5, 39.3) 34.9 (30.15, 38.8) 0.605
LDH, U/L, M (IQR) 221 (180,282) 279 (188, 413) 216.5 (174, 271.5) 0.038
CR, umol/L, M (IQR) 87 (68.25,117.75) 88 (76, 184) 87 (67, 114.5) 0.194
UREA, mmol/L, M (IQR) 8.9 (5.7,15.85) 14.1 (9.7, 26.35) 7.6 (5.2, 14.2) < 0.001
cTnI, pg/mL, M (IQR) 18.05 (6.35,197.875) 70.7 (11.2, 755.65) 13.8 (6.2, 162.7) 0.098
D2D, ug/mL FEU, M (IQR) 5.365 (1.46,19.045) 8.41 (2.47, 17.74) 4.5 (1.39, 19.06) 0.316
FT3, pmol/L, M (IQR) 2.665 (2.303,2.888) 2.68 (2.35, 2.92) 2.66 (2.31, 2.88) 0.696
FT4, pmol/L, M (IQR) 16.05 (13.623,18.345) 16.39 (13.53, 18.89) 16 (13.75, 18.25) 0.687
TSH, uIU/mL, M (IQR) 0.96 (0.412,1.848) 0.16 (0.10, 0.21) 1.29 (0.69, 2.03) /
  1. NTI non-thyroidal illness syndrome, M (IQR) Median (interquartile range), WBC white blood cell, LC leukomonocyte, CRP ultrasensitive C-reactive protein, PCT procalcitonin, ALT alanine aminotransferase, AST aspertate aminotransferase, ALB albumin, LDH lactate dehydrogenase, Cr Creatinine, UREA urea nitrogen, cTnI cardiac troponin I, D2D D dimmers