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Table 2 Determine points associated with each of the categories of each risk factor

From: Clinical risk score for central precocious puberty among girls with precocious pubertal development: a cross sectional study

Predictors

Categories

Reference value (Wij)

βi

βi (Wij-WiREF)

Pointsij = βi (Wij-WiREF)/B a

Age at onset of puberty (years)

< 1

0.5 = W1REF

0.45

0

0

1 - < 2

1.5

 

0.45

1

2 - < 3

2.5

 

0.90

3

3 - < 4

3.5

 

1.35

4

4 - < 5

4.5

 

1.80

6

5 - < 6

5.5

 

2.25

7

6 - < 7

6.5

 

2.70

8

7 - < 8

7.5

 

3.15

10

Basal LH (IU/L)

< 0.2

0.1 = W2REF

1.63

0

0

0.2 - < 0.4

0.3

 

0.326

1

0.4 - < 0.6

0.5

 

0.652

2

0.6 - < 0.8

0.7

 

0.978

3

0.8 - < 1.0

0.9

 

1.304

4

1.0 - < 1.2

1.1

 

1.630

5

1.2 - < 1.4

1.3

 

1.956

6

1.4 - < 1.6

1.5

 

2.282

7

1.6 - < 1.8

1.7

 

2.608

8

1.8 - < 2.0

1.9

 

2.934

9

2.0 - < 2.2

2.1

 

3.260

10

2.2 - < 2.4

2.3

 

3.586

11

2.4 - < 2.6

2.5

 

3.912

12

≥ 2.6

3.0

 

4.727

14

Largest ovarian volume

< 1 mL

1 = W3REF

0.66

0

0

1- < 2 mL

2

 

0.66

2

≥ 2 mL

3

 

1.32

4

Uterine volume

< 3 mL

1 = W4REF

0.85

0

0

3- < 4 mL

2

 

0.85

3

≥ 4 mL

3

 

1.70

5

  1. Points associated with each category of each risk factor are computed by: Pointsij = βi (Wij-WiREF)/B and rounded to the nearest integer
  2. aWe define the constant B for the points system (the number of regression units that will correspond to one point) as the increase in risk of CPP associated with a 0.2 (IU/L) increase in basal LH: B = 0.2*1.63 = 0.326