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Table 1 Clinical characteristics and main outcome in the non-GDM and GDM groups

From: The protective role of serum uric acid against premature membrane rupture in gestational diabetes: a cross-sectional study

Variable P-NGT group GDM group P-value
(n = 304) (n = 152)
Age (years) 29 (26, 32) 29 (26, 33) 0.171
Pre-pregnancy BMI (kg/m2) 21.23 (19.56, 23.24) 22.32 (20.20, 24.17) 0.001*
Systolic blood pressure (mmHg) 110 (104, 120) 112 (102, 120) 0.294
Diastolic blood pressure (mmHg) 70 (65, 75) 70 (65, 78) 0.673
HbA1c (%) 4.80 (4.50, 4.90) 4.90 (4.40, 5.20) < 0.001**
FPG (mmol/L) 4.20 (4.00, 4.50) 4.90 (4.40, 5.65) < 0.001**
1-h PG (mmol/L) 6.70 (5.70, 7.95) 9.80 (7.78, 10.90) < 0.001**
2-h PG (mmol/L) 6.30 (5.40, 6.90) 8.50 (6.13, 9.20) < 0.001**
FINS (mU/L) 8.72 (5.96, 12.98) 10.26 (6.69, 15.46) 0.010*
1-h INS (mU/L) 61.49 (42.55, 86.39) 74.00 (48.65, 117.00) 0.010*
2-h INS (mU/L) 60.70 (39.81, 82.71) 84.06 (51.94, 133.75) < 0.001**
HOMA-IR 1.64 (1.09, 2.51) 2.20 (1.46, 3.84) < 0.001**
HOM-AB 3.68 (1.73, 3.68) 1.75 (0.94, 2.56) < 0.001**
ALT (U/L) 15 (11, 23) 13 (10.00, 22) 0.301
Total bilirubin (μmol/L) 8.00 (6.90,10.00) 8.00 (6.25,9.69) 0.569
Creatinine (umol/L) 46 (43, 51) 47 (42, 51) 0.494
Uric acid (μmol/L) 213 (184,259) 230 (195,256) 0.130
Triglycerides (mmol/L) 2.17 (1.73,2.80) 2.41 (1.90,3.11) 0.023*
Total cholesterol (mmol/L) 6.07 (5.53, 6.82) 5.97 (5.27, 6.66) 0.093
White blood cell (× 109/L) 9.12 ± 2.02 9.90 ± 2.07 < 0.001*
Platelet count (×109/L) 217.50 ± 48.21 224.07 ± 42.06 0.061
Parity 2 (1,2) 1 (1,2) 0.439
Weight gain during pregnancy (Kg)
Systolic pressure before delivery (mmHg)
15.85 ± 5.37
120 (110,126)
14.09 ± 6.47
120 (117,127)
0.014*
0.135
Fetus birth weight (g) 3398.92 ± 461.79 3542.10 ± 448.09 0.003*
PROM (n,%) 22 (7.6) 19 (13.29) 0.033*
Macrosomia (n,%) 20 (6.99) 24 (16.78) 0.004*
Fetal distress in the uterus (n,%) 25 (8.74) 13 (0.091) 0.991
  1. Data represent the Mean and standard deviation, medians (interquartile ranges) or percentages (%). Significant at P < 0.05. P < 0.05*, P < 0.001**, Calculated using the Mann-Whitney U test or Chi-square test
  2. PROM premature rupture of the membranes, BMI body mass index, HbA1c hemoglobin, FPG fasting plasma glucose, 1-h PG 1-hour postprandial glucose, 2-h PG 2-hour postprandial glucose, FINS fasting insulin, 1-h INS 1-hour postprandial insulin, 2-h INS 2-hour postprandial insulin, ALT alanine aminotransferase, Macrosomia Fetus birth weight above 4000g