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Table 2 The associations of ApoA1, ApoB levels and ApoB/A1 ratio with T2D prevalence

From: Association of apolipoproteins A1 and B with type 2 diabetes and fasting blood glucose: a cross-sectional study

Variables

Quartiles by Apolipoproteins

p

Q1

Q2

Q3

Q4

ApoA1, g/L

 Mean (SD)

0.59 (0.20)

0.99 (0.10)

1.34 (0.10)

1.73 (0.16)

 

 Case/N

76/255

10/255

20/257

29/258

 

OR (95% CI)

 Model 1

1

0.09 (0.05, 0.18)**

0.20 (0.12, 0.35)**

0.29 (0.18, 0.46)**

< 0.001

 Model 2

1

0.15 (0.07, 0.33)**

0.37 (0.20, 0.68)**

0.60 (0.35, 1.02)

0.232

 Model 3

1

0.15 (0.07, 0.34)**

0.37 (0.20, 0.68)**

0.60 (0.35, 1.03)

0.232

ApoB, g/L

 Mean (SD)

0.77 (0.14)

1.03 (0.06)

1.23 (0.06)

1.60 (0.25)

 

 Case/N

17/262

25/252

46/260

47/253

 

OR (95% CI)

 Model 1

1

1.53 (0.80, 2.91)

2.91 (1.62, 5.24)**

3.09 (1.71, 5.55)**

< 0.001

 Model 2

1

1.68 (0.75, 3.79)

3.59 (1.72, 7.49)**

3.52 (1.67, 7.41)**

< 0.001

 Model 3

1

1.65 (0.73, 3.73)

3.49 (1.67, 7.31)**

3.38 (1.60, 7.14)**

< 0.001

ApoB/A1 ratio

 Mean (SD)

0.58 (0.08)

0.79 (0.07)

1.10 (0.13)

2.26 (0.95)

 

 Case/N

17/256

31/257

16/258

71/256

 

OR (95% CI)

 Model 1

1

1.82 (0.98, 3.38)

0.84 (0.41, 1.71)

5.12 (2.91, 9.02)**

< 0.001

 Model 2

1

1.56 (0.82, 2.97)

0.75 (0.36, 1.58)

2.53 (1.35, 4.73)**

0.023

 Model 3

1

1.50 (0.78, 2.87)

0.72 (0.34, 1.52)

2.39 (1.27, 4.52)*

0.036

  1. Model 1 was adjusted for age. Model 2 was adjusted for sex, age, BMI, education, marriage, exercise, cigarette smoking, alcohol consumption and hypoglycemic drugs use. Model 3 further adjusted for lipid-lowering drugs use
  2. Apo apolipoprotein, SD standard deviation, OR odds ratio, 95%CI 95% confidence interval, Q quartile, T2D type 2 diabetes
  3. *p < 0.05 compared with Q1
  4. **p < 0.001 compared with Q1