Table 1 Baseline Data
Measure | BMI ≥35 kg/m2 (n = 291) 42% | BMI < 35 kg/m2 (n = 409) 58% | P value |
|---|---|---|---|
Age | 56.1 ± 14.8 | 61.4 ± 14.6 | < 0.001 |
%Women | 53.3% (n = 155) | 42.3% (n = 173) | 0.004 |
Weight (kg) | 119.6 ± 24.3 | 81.9 ± 16.2 | < 0.001 |
BMI (kg/m2) | 42.5 ± 7.0 | 28.8 ± 3.8 | < 0.001 |
Duration of Diabetes (years) | 11.0 ± 9.0 | 12.3 ± 8.9 | 0.078 |
%Smoker/Ex-Smoker | 31% (n = 90) | 28% (n = 115) | 0.421 |
Hypertension | 70% (n = 202) | 66% (n = 268) | 0.270 |
Systolic BP | 131 ± 18 | 130 ± 18 | 0.265 |
Diastolic BP | 76 ± 11 | 75 ± 11 | 0.418 |
Dyslipidaemia | 59% (n = 171) | 59% (n = 241) | 0.939 |
Cholesterol Medication | 53% (n = 154) | 61% (n = 247) | 0.047 |
Total cholesterol | 4.5 ± 1.3 | 4.2 ± 1.4 | 0.138 |
LDL | 2.3 ± 1.0 | 2.2 ± 0.9 | 0.223 |
HDL | 1.1 ± 0.3 | 1.2 ± 0.9 | 0.504 |
Triglycerides | 2.8 ± 1.8 | 2.7 ± 3.4 | 0.786 |
Obstructive Sleep Apnoea | 25% (n = 73) | 6% (n = 24) | < 0.001 |
Ischaemic Heart Disease | 25% (n = 71) | 26% (n = 104) | 0.734 |
Stroke | 9.7% (n = 28) | 7.9% (n = 32) | 0.411 |
Chronic Kidney Disease Stage 3 or below | 19% (n = 55) | 22% (n = 91) | 0.261 |
eGFR | 70.2 ± 22.8 | 67.7 ± 23.9 | 0.217 |
Abnormal Urine ACR | 51% (n = 107) | 47% (n = 116) | 0.838 |
Peripheral Vascular Disease | 6.2% (n = 18) | 5.4% (n = 22) | 0.660 |
Peripheral Neuropathy | 18% (n = 52) | 18% (n = 73) | 0.987 |
Current/Previous Foot ulcer | 8.6% (n = 25) | 3.9% (n = 16) | 0.009 |
Previous lower limb amputations | 4.1% (n = 12) | 2.4% (n = 10) | 0.210 |
Laser treatment for Diabetic Retinopathy | 4.3% (n = 12) | 6.4% (n = 26) | 0.257 |
Depression | 16% (n = 46) | 11% (n = 44) | 0.049 |
Starting HbA1c | 75 ± 27 mmol/mol (9.0 ± 2.5%) | 72 ± 26 mmol/mol (8.7 ± 2.4%) | 0.118 |
% on Insulin | 62% (n = 180) | 58% (n = 235) | 0.252 |
Total daily dose of insulin (units) | 59.9 ± 49.3 | 37.2 ± 26.0 | 0.004 |