Fig. 3

The SOX9 immunohistochemistry. SOX9 differential protein expression was evaluated by immunohistochemistry in GH-secreting tumor tissues. a Normal pituitary tissue. The score 0; < 5% of neoplastic cells staining, absence of immunoreactivity, × 200., b GH-secreting tumor tissues. 1+; 5–25% of neoplastic cells staining, weak intensity of staining × 200. c GH-secreting tumor tissues. 2+; 26–50% of neoplastic cells staining, moderate intensity staining, × 200. d GH-secreting tumor tissues.2+; 26–50% of neoplastic cells staining, moderate intensity staining, × 200