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Table 2 Biochemical measures of all study subjects and separately in normal weight, overweight, and obese PCOS individuals (mean ± SD and median in brackets)

From: Insulin resistance and high molecular weight adiponectin in obese and non-obese patients with Polycystic Ovarian Syndrome (PCOS)

Variable

All participants

BMI groups

< 25

25–29.9

≥30

P-value*

Fasting glucose (mg/dl)

91.19 ± 7.83 (90.0)

90.59 ± 6.10 (90.0)

92.62 ± 10.34 (92.0)

90.27 ± 6.97 (89.0)

0.65

Total cholesterol (mg/dl)

170.55 ± 40.85 (172.0)

170.15 ± 50.59 (173.0)

177.23 ± 26.18 (174.0)

160.00 ± 32.53 (162.0)

0.37

HDL-cholesterol (mg/dl)

43.78 ± 9.28 (44.0)

44.72 ± 9.10 (46.0)

43.54 ± 11.12 (42.0)

41.73 ± 5.73 (43.0)

0.57

LDL-cholesterol (mg/dl)

70.56 ± 25.76 (70.0)

72.36 ± 32.73 (70.0)

71.27 ± 64.21 (70.0)

64.67 ± 21.02 (63.0)

0.46

Triglycerides (mg/dl)

121.48 ± 66.81 (101.0)

109.08 ± 61.67 (91.0)

147.04 ± 81.56 (125.0)

109.40 ± 34.45 (113.0)

0.04

Insulin level (μIU/mL)

10.84 ± 5.43 (9.2)

9.39 ± 4.47 (8.2)

12.17 ± 6.10 (12.7)

12.33 ± 5.88 (11.0)

0.13

HOMA-IR

2.4 ± 1.3 (2.0)

2.13 ± 1.10 (1.8)

2.81 ± 1.45 (3.0)

2.76 ± 1.37 (2.3)

0.13

TSH (ng/dl)

3.19 ± 2.02 (2.8)

3.18 ± 2.15 (2.9)

2.84 ± 1.39 (2.6)

3.85 ± 2.55 (3.0)

0.60

Prolactin (ng/ml)

9.54 ± 8.44 (7.6)

9.92 ± 7.64 (7.7)

10.50 ± 10.66 (8.9)

6.91 ± 5.58 (5.9)

0.38

LH (mIU/ml)

5.54 ± 4.37 (4.4)

6.26 ± 4.45 (4.8)

5.65 ± 5.07 (4.4)

3.51 ± 1.49 (4.0)

0.07

FSH (mIU/ml)

6.64 ± 2.40 (6.6)

6.81 ± 2.28 (6.8)

6.75 ± 2.35 (6.0)

6.03 ± 2.83 (6.0)

0.55

17(OH) progesterone (ng/ml)

1.63 ± 1.96 (1.2)

1.49 ± 0.84 (1.3)

1.97 ± 3.22 (1.1)

1.41 ± 1.02 (1.1)

0.50

Total Testosterone (nmol/l)

0.53 ± 0.25 (0.4)

0.56 ± 0.26 (0.5)

0.51 ± 0.26 (0.5)

0.51 ± 0.23 (0.5)

0.77

Free Androgen Index

1.67 ± 1.54)1.3)

1.47 ± 1.21 (1.2)

1.80 ± 2.06 (1.4)

2.02 ± 1.27 (1.6)

0.16

DHEAS (μmol/l)

3.18 ± 1.78 (3.2)

3.39 ± 2.09 (3.3)

3.11 ± 1.43 (3.0)

2.79 ± 1.48 (2.4)

0.45

SHBG (nmol/l)

48.09 ± 42.3 (35.0)

57.51 ± 53.3 (40.0)

43.86 ± 29.70 (36.0)

30.91 ± 15.54 (30.5)

0.04

HMWA (ng/ml)

2814.61 ± 1649.3 (2381.5)

3342.35 ± 1840.83 (2914.5)

2331.00 ± 1280.62 (1847.0)

2280.73 ± 1307.31 (1690.0)

0.03

  1. HDL High-Density Lipoprotein, LDL Low-Density Lipoprotein, HOMA-IR Homeostatic Model Assessment – Insulin Resistance, TSH Thyroid Stimulating Hormone, LH Luteinizing Hormone, FSH Follicle Stimulating Hormone, DHEAS DeHydroEpiandrosterone Sulfate, SHBG Sex Hormone Binding Globulin, HMWA High Molecular Weight Adiponectin. Free Androgen Index: (Testosterone /SHBG)*100
  2. * Difference between mean level, analyzed by ANOVA for normally distributed variables and kruskal-Wallis test for variables without normal distribution