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Table 2 Comparison of the incidence of metabolic syndrome between the higher-TH and the lower-TH groups

From: Lower normal free thyroxine is associated with a higher risk of metabolic syndrome: a retrospective cohort on Chinese population

 

Dividing cohorts into the higher-TH and the lower-TH groups according to cutoff values

P-value

TSH (mIU/L)

≤2.0

> 2.0

Participants/person-years

113/1164

141/1057

 

Model 1a

1.00

1.358 (1.060, 1.740)

0.015

Model 2b

1.00

1.308 (1.016, 1.683)

0.037

Model 3c

1.00

1.263 (0.972, 1.640)

0.081

T3 (nmol/L)

≤1.9

> 1.9

 

Participants/person-years

121/1165

133/1056

 

Model 1a

1.00

1.000 (0.781, 1.279)

0.997

Model 2b

1.00

1.016 (0.793, 1.302)

0.899

Model 3c

1.00

1.005 (0.781, 1.294)

0.969

T4 (nmol/L)

≤117

> 117

 

Participants/person-years

122/1065

132/1156

 

Model 1a

1.00

1.004 (0.785, 1.284)

0.975

Model 2b

1.00

0.967 (0.756, 1.238)

0.792

Model 3c

1.00

1.003 (0.779, 1.290)

0.984

FT3 (pmol/L)

≤4.3

> 4.3

 

Participants/person-years

85/839

95/870

 

Model 1a

1.00

1.078 (0.804, 1.445)

0.615

Model 2b

1.00

1.012 (0.753, 1.361)

0.937

Model 3c

1.00

1.054 (0.778, 1.429)

0.734

FT4 (pmol/L)

≤16

> 16

 

Participants/person-years

100/753

80/956

 

Model 1a

1.00

0.636 (0.474, 0.854)

0.003

Model 2b

1.00

0.619 (0.460, 0.832)

0.001

Model 3c

1.00

0.622 (0.458, 0.846)

0.002

  1. a Estimates were calculated in Cox proportional hazards models. Model 1, unadjusted
  2. b Model 2 was adjusted for sex and age based on model 1
  3. c Model 3 was further adjusted for BMI, PBG, LDL-C and GHB based on model 2