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Table 1 Baseline characteristics of enrolled participants and the association between two groups divided by thyroid function index

From: Lower normal free thyroxine is associated with a higher risk of metabolic syndrome: a retrospective cohort on Chinese population

Variablesa

Geometric Mean of Thyroid Function Index During Follow-up years

Basic cohort (929 participants/2221 person-years)

Second cohort (698 participants/1709 person-years)

TSH (mIU/L)

T3 (nmol/L)

T4 (nmol/L)

FT3 (pmol/L)

FT4 (pmol/L)

 

< 2.0

> 2.0

< 1.9

> 1.9

< 117

> 117

< 4.3

> 4.3

< 16

> 16

Number of participants

477

452

444

485

453

476

339

359

313

385

SEXa3 (Man/women)

384/93

319/133

320/124

383/102

338/115

365/111

243/96

306/53

235/78

314/71

Agea2 (years)

47.8 (13.9)

52.5 (14.3) b

51.3 (14.6)

49.0 (13.9) b

49.3 (14.1)

50.9 (14.4)

44.8 (8.5)

43.9 (9.9)

45.2 (8.7)

43.7 (9.7) b

BMI (kg/m2)

23.05 (3.31)

23.05 (3.68)

22.91 (3.63)

23.25 (3.47)

23.03 (3.26)

23.14 (3.77)

23.23 (3.86)

23.41 (3.32)

23.52 (3.58)

23.20 (3.42)

WC (cm)

85 (10)

85 (11)

85 (12)

85 (11)

85 (11)

85 (11)

85 (11)

86 (9) b

86 (9)

86 (10)

TG (mmol/l)

1.2 (0.7)

1.3 (0.7) b

1.2 (0.7)

1.3 (0.7) b

1.2 (0.7)

1.3 (0.7)

1.3 (0.7)

1.3 (0.8)

1.4 (0.7)

1.3 (0.7)

HDL-C (mmol/l)

1.3 (0.4)

1.3 (0.4)

1.3 (0.4)

1.3 (0.4)

1.3 (0.3)

1.3 (0.4)

1.3 (0.4)

1.3 (0.4)

1.3 (0.3)

1.3 (0.4)

DBP (mmHg)

74 (11)

75 (15)

76 (14)

74 (13)

74 (14)

75 (13)

74 (13)

75 (13)

75 (14)

74 (13)

SBP (mmHg)

117 (18)

118 (19)

117 (21)

118 (17)

116 (19)

118 (18)

114 (16)

116 (15)

115 (15)

116 (16)

GLU (mmol/l)

5.3 (0.6)

5.3 (0.5)

5.3 (0.6)

5.3 (0.6)

5.3 (0.6)

5.3 (0.6)

5.2 (0.6)

5.3 (0.6) b

5.3 (0.6)

5.3 (0.5)

PBG (mmol/l)

6.5 (1.7)

6.7 (1.8)

6.5 (1.9)

6.7 (1.7)

6.6 (1.8)

6.6 (1.9)

6.3 (1.6)

6.4 (1.7)

6.3 (1.6)

6.4 (1.8)

LDL (mmol/l)

2.5 (1.0)

2.5 (0.8)

2.5 (0.9)

2.5 (0.9)

2.4 (0.9)

2.6 (0.9) b

2.4 (0.8)

2.5 (0.9)

2.5 (0.9)

2.4 (0.8)

GHB (%)

4.4 (0.7)

4.4 (0.6)

4.4 (0.6)

4.4 (0.7)

4.4 (0.7)

4.4 (0.7)

4.4 (0.6)

4.4 (0.5)

4.4 (0.5)

4.4 (0.6)

  1. Abbreviations: BMI body mass index, BP blood pressure, DBP diastolic blood pressure, GLU glucose, GHB glycated hemoglobin, HDL high density lipoprotein, LDL low density lipoprotein, PBG postprandial blood glucose, SBP systolic blood pressure, TG triglyceride, WC waist circumference
  2. a Values are median (interquartile range) or means (standard deviations) a2 or ratio (men/women)a3 to the age distribution of the study population
  3. b Indicates that baseline characteristics divided by present thyroid function index were significantly different from each other (p < 0.05, Chi-square test, T-test, Non-parametric test)
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