Fig. 3

Daily injection frequency of injectable drugs and insulin dose at pretreatment and discharge. a Daily injection frequency of injectable drugs at maximal insulin dose (Max) and discharge. Dotted lines indicate integral numbers. b The number of patients whose daily injection frequency of injectable drugs was less than once per day (<1, black bar) and once per day or more (≥1, white bar). c Total insulin dose at Max and discharge, d basal insulin dose at Max and discharge, and (e) bolus insulin dose at Max and discharge. Daily injection frequency of Dula was calculated as 0.14 per day. Data are expressed as Tukey’s box-and-whisker plots. Pre, pretreatment. Max, maximal insulin dose. * p < 0.05 and *** p < 0.001 vs. Max of the same group. # p < 0.05, ## p < 0.01, and ### p < 0.001 vs. non-Dula group.