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Table 1 Baseline characteristics

From: Clinical and biochemical factors to predict biochemical adrenal insufficiency in hospitalized patients with indeterminate cortisol levels: a retrospective study

CharacteristicsBiochemical adrenal insufficiency (n = 36)No biochemical adrenal insufficiency (n = 92)p-value
Age (mean ± SD) (years)59.0 ± 17.055.2 ± 19.50.294
Male, n (%)17 (47.2)48 (52.1)0.431
Body weight (mean ± SD) (kg)53.8 ± 11.454.9 ± 14.30.712
Underlying diseases, n (%)
-Hypertension9 (25.0)21 (22.8)0.790
-Coronary artery disease6 (16.7)10 (10.8)0.372
-Autoimmune disease2 (5.5)9 (9.7)0.447
-Malignancy3 (8.3)13 (14.1)0.370
-Chronic renal disease2 (5.6)6 (6.5)0.846
-Cirrhosis/liver disease4 (11.1)3 (3.3)0.073
Indication of tests, n (%)
-History of exogenous steroid or traditional medicine use16 (44.4)22 (23.9)0.021
-Hyponatremia8 (22.2)11 (11.9)0.141
-Fatigue11 (30.5)21 (22.8)0.367
-Hypotension8 (22.2)14 (15.2)0.342
-Weight loss4 (11.1)4 (4.3)0.153
-Hypoglycemia1 (2.7)11 (11.9)0.104
Cushingoid appearance in patients with exogenous steroid and/or traditional medicine use, n (%)12 (33.3)6 (6.5)< 0.001
Ward, n (%)
-General medicine29 (80.6)76 (82.6) 
-Surgery7 (19.4)16 (17.4)0.782
Inpatient diagnosis
-Sepsis11 (30.6)25 (27.2) 
-Non-sepsis25 (69.4)67 (72.8)0.701
Length of hospital stay (mean ± SD) (days)22.3 ± 24.139.8 ± 41.60.349
Baseline SBP (mean ± SD) (mmHg)109.9 ± 17.5118.2 ± 21.90.060
Baseline DBP (mean ± SD) (mmHg)67.1 ± 10.271.2 ± 15.60.174
ACTH stimulation test dose, n (%)
-1 μg18 (50.0)39 (42.4) 
-250 μg18 (50.0)53 (57.6)0.432
Serum 0800 h cortisol (mean ± SD) (μg/dl)7.4 ± 3.210.3 ± 3.1< 0.001
Serum random cortisol (mean ± SD) (μg/dl)6.2 ± 3.411.6 ± 5.7< 0.001
Serum albumin (mean ± SD) (g/dl)2.9 ± 0.83.1 ± 0.70.162
Serum cholesterol (mean ± SD) (mg/dl)152.9 ± 45.6146.0 ± 55.10.484
Serum sodium (mean ± SD) (mmol/L)135.0 ± 6.6136.5 ± 6.20.225
Serum potassium (mean ± SD) (mmol/L)3.9 ± 0.63.9 ± 0.50.642
Serum creatinine (mean ± SD) (mg/dl)1.21 ± 1.11.23 ± 1.30.956
eGFR86.4 ± 43.799.1 ± 62.00.287