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Table 1 Clinical characteristics of study participants in three groups

From: Association between decreased thyroid stimulating hormone and hyperuricemia in type 2 diabetic patients with early-stage diabetic kidney disease

Parameters High SUA group (n = 101) Normal SUA group (n = 153) Control group (n = 85) P
Gender (M/F) 57/44 97/56 52/33 0.537
Age (years) 52.54 ± 11.04 53.10 ± 10.89 51.35 ± 10.77 0.494
BMI (kg/m2) 27.47 ± 4.83‡† 25.09 ± 4.42† 23.58 ± 3.05 < 0.001
SBP (mmHg) 117.05 ± 9.32 118.89 ± 8.68 118.28 ± 11.82 0.337
DBP (mmHg) 67.85 ± 8.20 68.66 ± 8.02 68.55 ± 7.84 0.718
TC (mmol/L) 4.83 ± 1.27† 4.79 ± 1.35† 4.33 ± 0.61 0.006
HDL-C (mmol/L) 1.03 ± 0.26† 1.09 ± 0.31† 1.54 ± 0.33 < 0.001
LDL-C (mmol/L) 2.78 ± 0.83† 2.76 ± 1.07† 2.39 ± 0.46 0.007
TG (mmol/L) 2.35 (1.51, 2.98)‡† 1.65 (1.12, 2.46)† 0.78 (0.62,1.12) < 0.001
FBG (mmol/L) 9.72 ± 2.17‡† 7.87 ± 2.57† 5.02 ± 0.34 < 0.001
HbA1c (%) 8.58 ± 1.93† 8.88 ± 2.05† 5.57 ± 0.39 < 0.001
FINS (mIU/L) 15.30 (10.45,19.65)† 15.10 (9.65,18.65)† 8.70 (5.37,12.40) < 0.001
HOMA-IR 5.51 (4.75, 7.72)‡† 4.68 (3.33, 6.53) † 1.99 (1.26, 2.76) < 0.001
CR (μmol/L) 74.26 ± 22.61‡† 61.11 ± 14.83 61.97 ± 11.29 < 0.001
eGFR (mL/min/1.73m2) 108.66 ± 37.07‡† 133.27 ± 33.97 128.70 ± 30.71 < 0.001
UACR (mg/g) 38.01 (33.16,94.46)† 37.76 (34.08,55.84)† 3.45 (1.79, 5.29) < 0.001
FT3 (pg/ml) 3.61 ± 0.52 3.50 ± 0.42 3.47 ± 0.37 0.068
FT4 (ng/dl) 1.37 ± 0.19‡† 1.25 ± 0.17 1.23 ± 0.14 < 0.001
TSH (μIU/ml) 1.54 (1.09, 2.27) ‡† 1.92 (1.25, 2.86) 2.03 (1.33, 2.95) < 0.001
SUA (μmol/L) 420.33 ± 70.05‡† 297.63 ± 71.79 277.10 ± 62.59 < 0.001
  1. Abbreviations: High SUA group Subjects with hyperuricemia in type 2 diabetic patients with early-stage diabetic kidney disease, Normal SUA group Subjects with normal SUA level in type 2 diabetic patients with early-stage diabetic kidney disease, Control group Control subjects, BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, TC Total cholesterol, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, TG Triglycerides, FBG Fasting blood glucose, HbA1c Glycated hemoglobin, FINS Fasting insulinm, HOMA-IR Homeostasis model assessment for insulin resistance, CR Creatinine, eGFR Estimated glomerular filtration rate, UACR Urinary albumin-to-creatinine ratio, FT3 Free triiodothyronine, FT4 Free thyroxine, TSH Thyroid stimulating hormone, SUA Serum uric acid
  2. P < 0.017 (0.05 divided by the times of comparison), significantly different compared with normal SUA group; † P < 0.017 (0.05 divided by the times of comparison), significantly different compared with control group