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Table 1 Characteristics of two study groups at the start of the current study

From: Control of Graves’ hyperthyroidism with very long-term methimazole treatment: a clinical trial

Variables

Continued MMI (n = 27)

Discontinued MMI (n = 32)

Age, year

53.1 ± 19.8

49.7 ± 12.4

Female, n (%)

19 (70)

22 (69)

High school diploma, n (%)

11 (41)

12 (38)

Goiter gradea, n (%)

 0 or 1

9 (33)

10 (31)

 2

18 (67)

22 (69)

Current smoking, n (%)

4 (15)

5 (16)

Ophthalmopathy, n (%)

4 (15)

5 (16)

fT4, pmol/L

16.1 ± 2.4

15.8 ± 2.6

T3, ng/dL

125 ± 21

132 ± 26

TSH, mIU/L

3.0 ± 0.6

2.9 ± 1.2

TRAb, IU/Lb

1.3 ± 0.6

1.1 ± 0.7

MMI dose, mg/day

3.4 ± 1.1

3.8 ± 1.2

Duration of MMI therapy, years

15.6 ± 1.9

12.8 ± 4.0

Comorbiditiesc, n (%)

7 (26)

9 (28)

  1. Abbreviations: MMI methimazole; fT4 free thyroxine; T3 triiodothyronine; TSH thyrotropin, TRAb TSH receptor antibody
  2. aGoiter size: Grade 0, thyroid is not palpable or visible; grade I, thyroid is easily palpable but not visible; grade 2, thyroid easily visible with the head in the normal position
  3. bSerum TRAb concentration was below 2.3 IU/L in all patients
  4. cComorbidities included documented diabetes, hypertension, or dyslipidemia
  5. P-value < 0.001