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Table 1 Study eligibility criteria

From: Upfront F18-choline PET/CT versus Tc99m-sestaMIBI SPECT/CT guided surgery in primary hyperparathyroidism: the randomized phase III diagnostic trial APACH2

Inclusion criteria

- Age 18 years or older

- Patients with PHPT needing parathyroidectomy

- Biological tests confirming PHPT diagnosis (elevated serum PTH and calcium levels)

- Negative pregnancy test upon inclusion in women of childbearing age

- Patients with health care insurance

- Signed informed consent

Exclusion criteria

- Known allergy for MIBI or FCH or one of its excipients

- Pregnant or breastfeeding women

- Previous history of parathyroid surgery

- Patients with multiple endocrine neoplasia type 1 (MEN1)

- Any medical conditions or associated psychopathology that may compromise patient’s ability to participate in study

- Patient deprived of freedom or under guardianship.