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Table 2 Comparison of parameters between elevated and decreased groups

From: Effect of sodium–glucose cotransporter-2 inhibitors on aldosterone-to-renin ratio in diabetic patients with hypertension: a retrospective observational study

 

Elevated Group

(n = 17)

Decreased Group

(n = 23)

Baseline

Change

Baseline

Change

Female, n (%)

8 (47)

 

11 (48)

 

Age

59.1 ± 13.6

 

57.2 ± 12.5

 

BW, kg

73.0 ± 19.3

−1.5 ± 1.9

80.5 ± 17

−1.2 ± 2.6

BMI, kg/m2

27.6 ± 4.4

−0.6 ± 0.8

30.7 ± 6.0

−0.5 ± 1.1

SBP, mmHg

129 ± 13

2 ± 15

130 ± 14

−6 ± 12

DBP, mmHg

79 ± 11

0 ± 7 *

81 ± 10

−6 ± 7

HR, bpm

85 ± 13 *

−6 ± 8

77 ± 11

−3 ± 8

Ht, mg/dL

41.3 ± 3.8

1.7 ± 2.1

43.8 ± 3.5

1.4 ± 1.8

s-Cr, mg/dL

0.74 ± 0.16

0.02 ± 0.06

0.72 ± 0.19

0.04 ± 0.08

eGFR, mL/min/1.73m2

78.4 ± 18.5

− 1.5 ± 10.6

83.4 ± 23.2

−3.6 ± 11.4

s-K, mEq/L

4.1 ± 0.3

0.1 ± 0.2

4.2 ± 0.3

0 ± 0.2

FPG, mg/dL

154 ± 42

−17 ± 37

159 ± 60

− 28 ± 51

HbA1c, %

8.2 ± 1.5

−0.8 ± 0.8

8.1 ± 1.2

−0.6 ± 0.8

PRA, ng/mL/h

3.3 ± 3.4

−0.2 ± 1.7

2.4 ± 2.7

1.4 ± 3.2

PAC, pg/mL

116 ± 56

30 ± 61

165 ± 161

−5 ± 134

ARR

67 ± 51

34 (8 to 60) ‡

109 ± 118

− 17 (− 48 to − 11)

Use of Ca-blocker, n (%)

8 (47)

 

11 (48)

 

Use of Alpha-blocker, n (%)

1 (6)

 

2 (9)

 

Use of beta-blocker, n (%)

1 (6)

 

0 (0)

 

Use of ARB/ACEI, n (%)

8 (47)

 

13 (57)

 

Use of diuretics, n (%)

2 (12)

 

2 (9)

 
  1. See Table 1 for abbreviations. Data are n (%), mean ± SD, or median (25th to 75th percentile)
  2. *, p < 0.05; ‡, p < 0.001 vs. Decreased group