Table 1 Characteristics of type 2 diabetes patients with and without CRC

Number of patients

50

100

–

Sex (male %)

66

54

0.160

Age (yr)

69.44 ± 7.73

67.29 ± 7.83

0.114

Duration of diabetes (yr)

11.50 (5.00–15.00)

10.00 (6.00–18.00)

0.743

BMI (kg/m2)

24.70 ± 2.04

25.25 ± 3.21

0.205

TG (mmol/L)

1.98 (1.64–2.33)

1.65 (1.08–2.30)

0.028

TC (mmol/L)

4.78 (4.33–5.04)

4.33 (3.43–4.98)

0.013

LDL-c (mmol/L)

2.64 ± 0.58

2.42 ± 0.83

0.061

HDL-c (mmol/L)

1.16 ± 0.40

1.16 ± 0.27

0.957

HOMA-IR

3.93 (2.43–5.46)

3.66 (1.75–5.61)

0.539

Fasting plasma glucose (mmol/L)

7.41 (5.92–9.47)

7.73 (6.27–9.37)

0.534

Fasting C-peptide (nmol/L)

0.83 (0.66–1.06)

0.74 (0.51–1.05)

0.096

Fasting serum insulin (pmol/L)

83.48 (63.47–109.38)

72.43 (43.22–100.78)

0.191

Hemoglobin A1c (%)

8.09 ± 0.79

8.47 ± 1.77

0.071

IL-6 (ng/L)

78.70 (58.23–114.17)

24.49 (14.00–36.05)

<0.001

sRAGE (ng/L)

604.61 ± 210.21

404.80 ± 166.18

<0.001

Current smoker (%)

26

15

0.103

Insulin use (%)

34

84

<0.001

Sulfonylurea use (%)

32

45

0.127

Metformin use (%)

16

83

<0.001

Thiazolidinedione use (%)

0

13

0.018

a-Glucosidase inhibitor use (%)

12

62

<0.001

NSAID use (%)

8

41

<0.001

Statin use (%)

6

40

<0.001