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Table 1 Gender differences at first clinical presentation of PES patients

From: Clinical presentation, evaluation and case management of primary empty sella syndrome: a retrospective analysis of 10-year single-center patient data

 

Total (765)

Male (158)

Female (607)

p value

Mean age (years) (Mean ± SD)

48.4 ± 14.8

46.7 ± 17.3

48.8 ± 14.1

0.110

Gender prevalence

158 (20.5)

607 (79.4)

0.000

Age-wise distribution:

 ≤ 29 years

87 (11.4)

30 (18.9)

57 (9.4)

0.022

 30-49 years

303 (39.6)

56 (35.2)

247 (40.7)

 

 ≥ 50 years

375 (49.0)

72 (45.3)

303 (49.)

 

 Asymptomatic

449 (58.6)

103 (64.8)

346 (57)

0.124

 Incidental finding

605 (79)

121 (76.1)

484 (79.7)

0.185

 Seen by endocrinologist

155 (20.2)

42 (26.4)

113 (18.6)

0.019

Common symptoms:

 Headache

227 (29.6)

29 (18.3)

198 (32.6)

0.001

 Vision disturbance

109 (14.2)

18 (11.3)

91 (15)

0.297

 Fatigue

33 (4.3)

7 (4.4)

26 (4.3)

0.596

 Galactorrhea

6 (0.8)

6 (1.0)

 

 Amenorrhea

5 (0.7)

5 (0.8)

 

 Irregular cycle

11 (1.4)

11 (1.8)

 

 Infertility

10 (1.3)

6 (3.8)

4 (0.7)

0.003

 Loss of libido

7 (1.0)

5 (3.1)

2 (0.3)

0.001

  1. Data is presented in number (%)
  2. The denominator for percentage calculation is based on gender total (Male158 and female: 607)