Table 1 Characteristics of patients with or without diabetic kidney disease
Variables | Patients without DKD (n = 945) | Patients with DKD (n = 265) | P value |
|---|---|---|---|
Age (years) | 65.24 (59.00 ~ 75.03) | 67.00 (59.70 ~ 79.00) | 0.005 |
Female (n, %) | 400 (42.33%) | 110 (41.51%) | 0.83 |
Smoking (n, %) | 275 (29.1%) | 76 (28.7%) | 0.90 |
Duration of T2DM (years) | 9.80 (5.35 ~ 14.25) | 9.10 (5.50 ~ 14.20) | 0.71 |
BMI (kg/m2) | 25.00 (22.25 ~ 27.85) | 24.9 (21.90 ~ 28.10) | 0.74 |
Hypertension (%) | 598 (63.28%) | 221 (83.40%) | < 0.001 |
Medicine used (n, %) | |||
Metformin | 502 (53.1%) | 107 (40.4%) | < 0.001 |
Thiazolidinediones | 35 (3.7%) | 11 (4.2%) | 0.74 |
Statins | 402 (42.5%) | 123 (46.4%) | 0.26 |
Aspirin | 236 (25.0%) | 85 (32.1%) | 0.021 |
RASi | 365 (40.7%) | 151 (57.0%) | < 0.001 |
ESR (mm/h) | 12.00 (7.00 ~ 22.00) | 23.00 (12.00 ~ 41.50) | < 0.001 |
hsCRP (mg/L) | 2.90 (1.80 ~ 5.60) | 3.60 (2.20 ~ 7.65) | < 0.001 |
WBC (× 109/L) | 6.43 (5.35 ~ 7.76) | 6.66 (5.60 ~ 8.01) | 0.039 |
NEU (%) | 58.35 (52.03 ~ 64.60) | 61.50 (55.45 ~ 68.80) | < 0.001 |
Hb (g/L) | 134.00 (123.00 ~ 146.00) | 127.00 (114.00 ~ 136.50) | < 0.001 |
ALB(g/L) | 37.00 (35.00 ~ 40.00) | 35.00 (31.00 ~ 38.00) | < 0.001 |
GLB(g/L) | 27.00 (24.00 ~ 30.00) | 28.00 (25.00 ~ 31.00) | < 0.001 |
HbA1c (%) | 8.20 (7.00 ~ 9.90) | 8.60 (7.30 ~ 10.10) | 0.10 |
FBG (mmol/L) | 7.26 (5.82 ~ 9.67) | 7.90 (6.10 ~ 10.93) | 0.017 |
TC (mmol/L) | 4.26 (3.57 ~ 5.07) | 4.46 (3.73 ~ 5.39) | 0.006 |
TG (mmol/L) | 1.33 (0.92 ~ 1.97) | 1.52 (1.01 ~ 2.22) | 0.002 |
HDL (mmol/L) | 0.97 (0.84 ~ 1.15) | 0.92 (0.80 ~ 1.08) | < 0.001 |
LDL (mmol/L) | 2.38 (1.82 ~ 3.03) | 2.60 (1.83 ~ 3.29) | 0.005 |
ACR (mg/g) | 12.56 (7.04 ~ 27.38) | 394.49 (96.64 ~ 1316.90) | < 0.001 |
SCr (μmol/L) | 67.84 (56.00 ~ 79.93) | 84.00 (64.50 ~ 108.40) | < 0.001 |
eGFR (ml/min/1.73m2) | 92.04 (78.10 ~ 101.72) | 75.69 (48.13 ~ 95.18) | < 0.001 |