Table 2 Clinical characteristics of participants
CRC (−) (n = 27,805) | CRC (+) (n = 116) | P-value | |
|---|---|---|---|
Sex, men/women | 16,353/11,452 | 81/35 | 0.014 |
Age, yrs | 45.6 (10.1) | 51.1 (9.3) | < 0.001 |
BMI, kg/m2 | 22.6 (3.3) | 23.1 (3.5) | 0.084 |
WC, cm | 78.0 (9.6) | 80.5 (8.9) | 0.006 |
Smoking status | – | – | 0.003 |
Non-smoker | 14,772 (53.0) | 43 (37.1) | – |
Ex-smoker | 6150 (22.1) | 35 (30.2) | – |
Current smoker | 6883 (24.8) | 38 (32.8) | – |
Regular exerciser | 4964 (18.0) | 20 (17.5) | 0.905 |
Alcohol consumption | – | – | < 0.001 |
Light alcohol consumer | 4682 (17.0) | 23 (20.0) | – |
Moderate alcohol consumer | 2560 (9.3) | 17 (14.8) | – |
Heavy alcohol consumer | 2177 (7.9) | 21 (18.3) | – |
Fasting plasma glucose, mmol/L | 5.4 (1.0) | 5.7 (1.4) | 0.004 |
HbA1c, % | 5.3 (0.6) | 5.4 (0.8) | 0.042 |
HbA1c, mmol/mol | 34.6 (6.8) | 35.9 (8.2) | 0.042 |
Triglycerides, mmol/L | 1.0 (0.9) | 1.3 (1.0) | 0.002 |
Total cholesterol, mmol/L | 5.2 (0.9) | 5.4 (0.9) | 0.011 |
HDL cholesterol, mmol/L | 1.4 (0.4) | 1.3 (0.4) | 0.012 |
Creatinine, μmol/L | 73.0 (22.8) | 76.7 (16.1) | 0.039 |
AST, IU/L | 19.5 (9.7) | 19.1 (7.6) | 0.664 |
ALT, IU/L | 21.5 (15.2) | 20.9 (9.2) | 0.689 |
GGT, IU/L | 23.6 (25.2) | 28.1 (32.3) | 0.053 |
SBP, mmHg | 117.7 (16.4) | 121.2 (17.1) | 0.018 |
DBP, mmHg | 73.6 (11.2) | 76.7 (11.0) | 0.004 |
TyG index | 8.2 (0.7) | 8.4 (0.7) | < 0.001 |