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Table 2 Indirect markers of IR in patients with T1D with or without MS

From: Comparison of indirect markers of insulin resistance in adult patients with Double Diabetes

 

Total population

Without MS (n = 75)

With MS (n = 37)

pa

eGDR, mg/kg/min

8.39 (6.53–9.68)

8.93 (8.03–9.94)

5.49 (4.37–6.80)

< 0.001

Female

8.47 (6.79–9.92)

9.68 (8.35–10.15)

6.32 (5.1–6.99)

< 0.001

Male

7.78 (5.47–8.79)

8.69 (7.37–9.2)

4.41 (3.91–6.48)

< 0.001

WHtR

0.52 ± 0.06

0.50 ± 0.05

0.55 ± 0.05

0.001

eIS

3.27 (2.30–4.31)

3.51 (2.68–4.68)

2.89 (1.54–3.54)

0.007

Female

3.31 (2.42–4.19)

3.68 (2.72–4.33)

2.96 (1.27–3.54)

0.009

Male

3.14 (2.24–5.1)

3.40 (2.28–5.27)

2.85 (1.78–4.73)

NS

lnGDR, mg/kg/min

1.86 ± 0.27

1.95 ± 0.21

1.69 ± 0.27

< 0.001

Female

1.87 ± 0.26

1.96 ± 0.22

1.69 ± 0.27

0.001

Male

1.83 ± 0.27

1.93 ± 0.22

1.67 ± 0.29

0.016

TG/HDL-c

2.15 (1.38–3.65)

1.77 (1.18–2.75)

3.78 (2.63–5.73)

< 0.001

Female

1.99 (1.35–3.66)

1.51 (1.10–2.15)

3.99 (2.76–5.78)

< 0.001

Male

2.53 (1.60–3.70)

2.08 (1.32–3.21)

3.78 (2.53–5.22)

0.005

VAI

1.76 (1.13–2.99)

1.39 (0.97–1.92)

3.4 (1.92–5.70)

< 0.001

  1. Data are presented as median (IQR) or mean ± SD. aStatistically different among patients with or without MS with Student t test or Mann Whitney U according to their distribution. eGDR estimated glucose disposal rate, WHtR waist-to-height ratio, eIS estimated insulin sensitivity, lnGDR natural logarithm of glucose disposal rate, TG/HDL-c ratio triglycerides/HDL cholesterol, VAI visceral adiposity index