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Table 2 The comparation of early hypothyroid risk factors between non-hypothyroid group and hypothyroid group

From: Predictive factors for early hypothyroidism following the radioactive iodine therapy in Graves’ disease patients

Variables

Non-hypothyroid

Hypothyroid

P value

Male: Female

4: 90

50: 168

0.001

Age (years)

43.82 ± 13.17

45.60 ± 12.63

0.261

Duration of Graves’ hyperthyroidism (months)

12 (1, 240)

6 (1, 376)

0.019

ATD therapy history: Non-ATD therapy history

63: 20

184: 45

0.393

Thyroid weight (g)

60.83 (23.02, 239.00)

49.82 (19.12, 163.3)

0.001

FT3 (pmol/L)

22.48 (4.68, 36.70)

21.33 (4.35, 36.69)

0.341

FT4 (pmol/L)

57.75 (3.51, 154.80)

49.55 (13.04, 154.80)

0.091

TSH (uIU/mL)

0.005 (0.001, 0.100)

0.005 (0.001, 0.250)

0.304

TPOAb (IU/mL)

1300 (23.30, 1300.00)

1300 (27.00, 1300.00)

0.514

TRAb (IU/mL)

13.56 (0.30, 40.00)

12.72 (0.30, 40.00)

0.601

2-h RAIU

39.86 (7.80, 83.69)

35.49 (9.01, 81.98)

0.009

6-h RAIU

70.38 (14.40, 95.62)

65.41 (16.53, 95.51)

0.001

24-h RAIU

74.20 (29.10, 99.90)

71.37 (27.29, 97.11)

0.008

6/24-h uptake ratio

94.59 (49.48, 115.87)

90.94 (51.77, 126.70)

0.015

Dose of RAI (mCi)

9.48 ± 3.08

8.52 ± 2.78

0.007

  1. FT3 Free triiodothyronine; FT4 Free thyroxine; TSH Thyrotropin; TPOAb Thyroperoxidase antibody; TRAb Thyrotropin receptor antibody; RAIU Radioactive iodine uptake