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Table 1 Clinical and biochemical characteristics of the subjects

From: Vitamin D receptor and binding protein polymorphisms in women with polycystic ovary syndrome: a case control study

 

PCOS (n = 432)

Control (n = 927)

P-value

Age (years)

24 ± 5

27 ± 5

< 0.001

Body mass index (kg/m2)

24.0 ± 4.7

21.1 ± 2.6

< 0.001

Waist circumference (cm)

79 ± 11

73 ± 7

< 0.001

Systolic blood pressure (mmHg)

111 ± 10

107 ± 9

< 0.001

Diastolic blood pressure (mmHg)

72 ± 9

69 ± 8

< 0.001

Sex hormone-binding protein (nmol/l)

45.8 ± 22.8

108.5 ± 62.2

< 0.001

Total testosterone (ng/dl)

76.7 ± 18.6

45.9 ± 15.4

< 0.001

Free testosterone (ng/dl)

1.20 ± 0.43

0.40 ± 0.20

< 0.001

Free androgen index

7.5 ± 4.9

1.9 ± 1.2

< 0.001

Fasting glucose (mg/dL)

87 ± 16

85 ± 7

0.006

Postload 2-h glucose (mg/dL)

112 ± 40

96 ± 19

< 0.001

Fasting insulin (mIU/L)

8.8 (6.3, 12.8)

3.1 (0.4, 6.7)

< 0.001

Postload 2-h insulin (mIU/L)

50.0 (29.9, 88.2)

20.5 (12.1, 35.7)

< 0.001

HOMA-IR

1.83 (1.30, 2.75)

0.63 (0.08, 1.44)

< 0.001

  1. Values are presented as mean ± SD or median (interquartile range)
  2. PCOS polycystic ovary syndrome, HOMA-IR homeostasis model assessment of insulin resistance