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Fig. 3 | BMC Endocrine Disorders

Fig. 3

From: CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation

Fig. 3

Effect of SPRY2 KO on transcript levels in HepG2 cells by RNA-Seq. a Volcano plot depicting up- and downregulated genes (green) resulting from SPRY2 KO in HepG2 cells. b Principal component analysis (PCA) showing separation of mock and SPRY2 KO samples along the major PC1 axis. c Clustering of the top 100 differentially expressed genes indicating separation of mock and SPRY2 KO samples. d MA plot showing relationship between P value and fold change; DE genes are labelled in red

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BMC Endocrine Disorders

ISSN: 1472-6823

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