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Table 2 Association of hypoglycaemia awareness determined by Clarke’s method with different variables

From: Impaired awareness of hypoglycemia in children and adolescents with type 1 diabetes mellitus in north of Jordan

 

Aware (n = 79)

IAH

(n = 15)

P-value*

Age (Years)

10 (8–13)

10 (5–11)

0.13

Gender

 Male

42 (53.2)

9 (60)

0.78

 Female

37 (46.8)

6 (40)

 

BMI (Kg/m2)

19.5 (16.6–23.9)

17.8 (16.5–23)

0.36

Duration of DM (Years)

2 (1–4)

1 (1–7)

0.48

Duration of insulin therapy (Years)

2 (1–4)

1 (1–7)

0.48

HbA1c (%)

8.5 (7.7–9.2)

8 (6–9)

0.12

Insulin regimen

  

0.56

 Mixtard insulin (regular insulin + isophane insulin)

73 (92.4)

15 (100)

 

 Regular insulin + Insulin Glargine

6 (7.6)

0 (0)

 

Adherence to insulin administration

 Not completely adherent

28 (35.4)

1 (6.7)

 

 Completely adherent

51 (64.6)

14 (93.3)

0.06

Maintaining regular meals after insulin administration

 Always

58 (73.4)

11 (73.3)

1.00

 Sometimes

21 (26.6)

4 (26.7)

 

Frequency of hypoglycemia during the previous 6 months

  ≤ Once/month

32 (40.5)

0 (0)

< 0.01

  > Once/month

47 (59.5)

15 (100)

 

Development of severe hypoglycemia during the previous year

 Yes

12 (15.2)

5 (33.3)

0.14

 No

67 (84.8)

10 (66.7)

 
  1. * Mann Whitney U test was used to find differences between aware and IAH participants in continuous variables, Chi-square test or Fisher’s exact test were used to find association between hypoglycemia awareness and categorical variables (P < 0.05 is considered significant). Data are expressed as median (25th–75th percentile) for continuous variables and as frequency (%) for categorical variables. IAH: impaired awareness of hypoglycemia