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Table 1 US patterns and estimated risk of malignancy proposed by American Thyroid Association ATA, 2015

From: ACR TI-RADS and ATA US scores are helpful for the management of thyroid nodules with indeterminate cytology

Benign - Estimated risk of malignancy < 1%

US features: Purely cystic nodules (no solid component)

Very low suspicion risk - Estimated risk of malignancy < 3%

US features: Spongiform or partially cystic nodules without any of US features defining low-, intermediate- or high-suspicion patterns

Low suspicion risk - Estimated risk of malignancy 5–10%

US features: Iso- or hyperechoic solid nodule, or partially cystic nodule with eccentric solid areas, without microcalcification, irregular margins, extrathyroidal extension (ETE) or taller-than-wide shape

Intermediate suspicion risk - Estimated risk of malignancy 10–20%

US features: Hypoechoic solid nodule with smooth margins without microcalcification, ETE or taller-than-wide shape

High suspicion risk - Estimated risk of malignancy > 70–90%

US features: Solid hypoechoic nodule or solid hypoechoic component of a partially cystic nodule with one or more of the following features: irregular margins (microlobulated, infiltrative), microcalcification, taller-than-wide shape, rim calcifications with small extrusive soft tissue component or ETE